A novel FY allele in Brazilians

The GATA box single nucleotide polymorphism (SNP) at position −33 (T>C) in Blacks silences the expression of FY*B in erythrocytes, and the substitution 265 C>T, together with 298 G>A, weakens the Fyb antigen (Fyx). Individuals with these phenotypes/genotypes who receive Fy(b+) blood are unl...

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Veröffentlicht in:	Vox sanguinis 2004-10, Vol.87 (3), p.190-195
Hauptverfasser:	Castilho, L., Rios, M., Pellegrino Jr, J., Saad, S. T. O., Costa, F. F., Reid, M. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	African Continental Ancestry Group - genetics Alleles Base Sequence Brazil Brazilians DNA - genetics Duffy blood group system Duffy Blood-Group System - genetics Duffy prevalence in Brazilians European Continental Ancestry Group - genetics FY gene Fyx Gene Frequency Gene Silencing Genotype Humans Phenotype Polymorphism, Single Nucleotide prevalence of Duffy gene Receptors, Cell Surface - genetics
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