GATA-4 regulation of myocardial survival in the preconditioned heart

Recent studies identified that GATA-4 is a stress responsive transcription factor and can exert cell survival signaling in cardiac myocytes. The present study was designed to examine whether GATA-4 is modulated by ischemic preconditioning (PC), and ischemia/reperfusion (I/R). PC of isolated rat hear...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2004-12, Vol.37 (6), p.1195-1203
Hauptverfasser:	Suzuki, Yuichiro J., Nagase, Hiroko, Day, Regina M., Das, Dipak K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Apoptosis Apoptosis - physiology Carbazoles - pharmacology Cardiac muscle Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors Cyclic GMP-Dependent Protein Kinases - metabolism DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - metabolism GATA-4 GATA4 Transcription Factor Indoles - pharmacology Ischemia Ischemic Preconditioning, Myocardial Male Myocardium - metabolism Nitric oxide Nitric Oxide - metabolism Preconditioning Protein Processing, Post-Translational - physiology Rats Rats, Sprague-Dawley Transcription Factors - biosynthesis Transcription Factors - metabolism
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