Behavioral response of human spermatozoa to a concentration jump of chemoattractants or intracellular cyclic nucleotides

BACKGROUND A major question in mammalian sperm chemotaxis is whether the cells sense a chemoattractant gradient by comparing the chemoattractant concentration between time points or between spatial points. METHODS To resolve this question, we exposed human spermatozoa to a temporal chemoattractant g...

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