Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells

Prominin‐1 (CD133) is a cholesterol‐interacting pentaspan membrane glycoprotein specifically associated with plasma membrane protrusions. Prominin‐1 is expressed by various stem and progenitor cells, notably neuroepithelial progenitors found in the developing embryonic brain. Here, we further invest...

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Veröffentlicht in:	Glia 2009-06, Vol.57 (8), p.860-874
Hauptverfasser:	Corbeil, Denis, Joester, Angret, Fargeas, Christine A., Jászai, József, Garwood, Jeremy, Hellwig, Andrea, Werner, Hauke B., Huttner, Wieland B.
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Animals Animals, Newborn Antigens, CD - genetics Antigens, CD - metabolism astrocyte Basic Helix-Loop-Helix Transcription Factors - metabolism Brain - cytology Brain - metabolism Cells, Cultured Cercopithecus aethiops Gene Expression Regulation, Developmental - genetics Glial Fibrillary Acidic Protein - metabolism Glycoproteins - genetics Glycoproteins - metabolism Kidney - cytology membrane protrusion Mice Mice, Jimpy Mice, Mutant Strains Microscopy, Immunoelectron - methods Myelin Basic Protein - deficiency Myelin Basic Protein - metabolism Myelin Proteolipid Protein - genetics Myelin Proteolipid Protein - metabolism myelin sheath Nerve Tissue Proteins - metabolism Neuroglia - metabolism Neuroglia - ultrastructure oligodendrocyte Oligodendrocyte Transcription Factor 2 Optic Nerve - metabolism Optic Nerve - ultrastructure Peptides - genetics Peptides - metabolism prominin Protein Isoforms - genetics Protein Isoforms - metabolism Transfection
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