Characterization and functional analysis of the 5′ flanking region of Sparus aurata myostatin-1 gene

Myostatin (MSTN) is a member of the transforming growth factor-β superfamily that functions as a negative regulator of skeletal muscle development and growth in mammals. Although several MSTN promoters were described in fish, no functional analysis was reported so far. Here, the 5′ flanking region (...

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Veröffentlicht in:	Comparative biochemistry and physiology. Part A, Molecular & integrative physiology Molecular & integrative physiology, 2009-05, Vol.153 (1), p.55-62
Hauptverfasser:	Funkenstein, Bruria, Balas, Viki, Rebhan, Yanai, Pliatner, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Flanking Region - genetics Animals Base Sequence Binding Sites Cell Line Conserved Sequence Human rhabdomyosarcoma A204 cell line Luciferase reporter gene assay Marine Molecular Sequence Data Myostatin - genetics Myostatin promoter Promoter Regions, Genetic - genetics Sea Bream - genetics Sequence Homology, Nucleic Acid Sparus aurata Transcription factors Transcription Factors - metabolism
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