DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen

BACKGROUND Epigenetic regulation may be involved in modulation of gene expression during the normal cyclic changes of the human endometrium. We investigated expression of DNA methyltransferases (DNMTs) in endometrium during the menstrual cycle and the influence of sex steroid hormones on DNMT in end...

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Veröffentlicht in:	Human reproduction (Oxford) 2009-05, Vol.24 (5), p.1126-1132
Hauptverfasser:	Yamagata, Yoshiaki, Asada, Hiromi, Tamura, Isao, Lee, Lifa, Maekawa, Ryo, Taniguchi, Ken, Taketani, Toshiaki, Matsuoka, Aki, Tamura, Hiroshi, Sugino, Norihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cells, Cultured decidualization DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases - genetics DNA (Cytosine-5-)-Methyltransferases - metabolism DNA methyltransferase DNA Methyltransferase 3A DNA Methyltransferase 3B Down-Regulation endometrial stromal cell endometrium Endometrium - cytology Endometrium - drug effects Endometrium - metabolism Estrogens - pharmacology Female Gene Expression Gonadal Steroid Hormones - pharmacology Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Medical sciences Menstrual Cycle - genetics Menstrual Cycle - metabolism Middle Aged Progesterone - pharmacology RNA, Messenger - metabolism Stromal Cells - metabolism
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