Do the Age of Patients with Tetralogy of Fallot at the Time of Surgery and the Applied Surgical Technique Influence the Reoperation Rate?: A Single-Center Experience
Background and Purpose: Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence o...
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Veröffentlicht in: | Herz 2009-03, Vol.34 (2), p.155-160 |
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creator | Gerling, Christoph Rukosujew, Andreas Kehl, Hans-Gerd Tjan, Tonny D. T. Hoffmeier, Andreas Vogt, Johannes Scheld, Hans-Heinrich Krasemann, Thomas |
description | Background and Purpose:
Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence on the long-term results.
Patients and Methods:
Between 1992 and 2003, 124 patients underwent complete repair of TOF at the University Hospital Münster, Germany. Patients were subdivided into two groups based on their age (< 1 year and > 1 year of age). Patients in whom a transannular patch (TAP) was used were compared with those without (NTAP), or in whom a conduit was used.
Results:
Overall mortality was 8%, with an average age of death of 9.53 years (range 0.06–19.77 years). The patients’ age at the time of surgery affected their survival as only two cases of death were reported among the group of children < 1 year of age (3.2%) whereas eight patients were older (12.9%; p = 0.0483). Six patients died within the first 30 days post surgery. Reoperation had to be performed in 21 cases, 13 (61.9%) of these patients were < 1 year of age at the time of surgery, eight were older (38.1%). A TAP, NTAP or conduit treatment did not show significant differences in long-term survival or freedom from reoperation.
Conclusion:
Early repair of TOF within the 1st year of life can be recommended, because mortality is lower than in patients treated at a higher age. There seems no significant difference in the reintervention rate between patients treated within the 1st year of life or later. |
doi_str_mv | 10.1007/s00059-009-3169-x |
format | Article |
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Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence on the long-term results.
Patients and Methods:
Between 1992 and 2003, 124 patients underwent complete repair of TOF at the University Hospital Münster, Germany. Patients were subdivided into two groups based on their age (< 1 year and > 1 year of age). Patients in whom a transannular patch (TAP) was used were compared with those without (NTAP), or in whom a conduit was used.
Results:
Overall mortality was 8%, with an average age of death of 9.53 years (range 0.06–19.77 years). The patients’ age at the time of surgery affected their survival as only two cases of death were reported among the group of children < 1 year of age (3.2%) whereas eight patients were older (12.9%; p = 0.0483). Six patients died within the first 30 days post surgery. Reoperation had to be performed in 21 cases, 13 (61.9%) of these patients were < 1 year of age at the time of surgery, eight were older (38.1%). A TAP, NTAP or conduit treatment did not show significant differences in long-term survival or freedom from reoperation.
Conclusion:
Early repair of TOF within the 1st year of life can be recommended, because mortality is lower than in patients treated at a higher age. There seems no significant difference in the reintervention rate between patients treated within the 1st year of life or later.</description><identifier>ISSN: 0340-9937</identifier><identifier>EISSN: 1615-6692</identifier><identifier>DOI: 10.1007/s00059-009-3169-x</identifier><identifier>PMID: 19370333</identifier><identifier>CODEN: HERZDW</identifier><language>eng</language><publisher>Munchen: Urban and Vogel</publisher><subject>Adolescent ; Age Distribution ; Cardiology ; Cardiovascular Surgical Procedures - statistics & numerical data ; Child ; Child, Preschool ; Female ; Germany - epidemiology ; Humans ; Infant ; Infant, Newborn ; Internal Medicine ; Longitudinal Studies ; Male ; Medicine ; Medicine & Public Health ; Patient Selection ; Reconstructive Surgical Procedures - statistics & numerical data ; Reoperation ; Risk Assessment - methods ; Risk Factors ; Survival Analysis ; Survival Rate ; Tetralogy of Fallot - mortality ; Tetralogy of Fallot - surgery ; Treatment Outcome ; Young Adult</subject><ispartof>Herz, 2009-03, Vol.34 (2), p.155-160</ispartof><rights>Urban & Vogel, Muenchen 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00059-009-3169-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00059-009-3169-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19370333$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gerling, Christoph</creatorcontrib><creatorcontrib>Rukosujew, Andreas</creatorcontrib><creatorcontrib>Kehl, Hans-Gerd</creatorcontrib><creatorcontrib>Tjan, Tonny D. T.</creatorcontrib><creatorcontrib>Hoffmeier, Andreas</creatorcontrib><creatorcontrib>Vogt, Johannes</creatorcontrib><creatorcontrib>Scheld, Hans-Heinrich</creatorcontrib><creatorcontrib>Krasemann, Thomas</creatorcontrib><title>Do the Age of Patients with Tetralogy of Fallot at the Time of Surgery and the Applied Surgical Technique Influence the Reoperation Rate?: A Single-Center Experience</title><title>Herz</title><addtitle>Herz</addtitle><addtitle>Herz</addtitle><description>Background and Purpose:
Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence on the long-term results.
Patients and Methods:
Between 1992 and 2003, 124 patients underwent complete repair of TOF at the University Hospital Münster, Germany. Patients were subdivided into two groups based on their age (< 1 year and > 1 year of age). Patients in whom a transannular patch (TAP) was used were compared with those without (NTAP), or in whom a conduit was used.
Results:
Overall mortality was 8%, with an average age of death of 9.53 years (range 0.06–19.77 years). The patients’ age at the time of surgery affected their survival as only two cases of death were reported among the group of children < 1 year of age (3.2%) whereas eight patients were older (12.9%; p = 0.0483). Six patients died within the first 30 days post surgery. Reoperation had to be performed in 21 cases, 13 (61.9%) of these patients were < 1 year of age at the time of surgery, eight were older (38.1%). A TAP, NTAP or conduit treatment did not show significant differences in long-term survival or freedom from reoperation.
Conclusion:
Early repair of TOF within the 1st year of life can be recommended, because mortality is lower than in patients treated at a higher age. There seems no significant difference in the reintervention rate between patients treated within the 1st year of life or later.</description><subject>Adolescent</subject><subject>Age Distribution</subject><subject>Cardiology</subject><subject>Cardiovascular Surgical Procedures - statistics & numerical data</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Germany - epidemiology</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Internal Medicine</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Patient Selection</subject><subject>Reconstructive Surgical Procedures - statistics & numerical data</subject><subject>Reoperation</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Survival Analysis</subject><subject>Survival Rate</subject><subject>Tetralogy of Fallot - mortality</subject><subject>Tetralogy of Fallot - surgery</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0340-9937</issn><issn>1615-6692</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kcFq3DAQhkVpabZpH6CXInrIze1IsuXVqYQ0aQOBhHR7FrI93nXQSq4k091H6FtXu14IFHoamPn-f4b5CXnP4BMDqD9HAKhUAaAKwaQqdi_IgklWFVIq_pIsQJRQKCXqM_ImxicAVikOr8kZyz0QQizIn6-epg3SyzVS39MHkwZ0KdLfQ9rQFaZgrF_vD6MbY61P1KQjvxq2R8GPKawx7Klx3ewzjnbA7tgfWmOzR7txw68J6a3r7YSuxSP4iH7EkNd5Rx9Nwi9vyave2IjvTvWc_Ly5Xl19L-7uv91eXd4VLZNyV5iaVdCI2kALTamg6XpcgjS1ELzkDVv2UsmGNwIYr7qlhJqbJWszjn3Ts1Kck4vZdww-nxWT3g6xRWuNQz9FLWvGRcUggx__AZ_8FFy-TXOoy0qxssoQm6E2-BgD9noMw9aEvWagDyHpOSSdQ9KHkPQuaz6cjKdmi92z4pRKBvgMxDxy-b_Pm__v-hdC_5zb</recordid><startdate>200903</startdate><enddate>200903</enddate><creator>Gerling, Christoph</creator><creator>Rukosujew, Andreas</creator><creator>Kehl, Hans-Gerd</creator><creator>Tjan, Tonny D. T.</creator><creator>Hoffmeier, Andreas</creator><creator>Vogt, Johannes</creator><creator>Scheld, Hans-Heinrich</creator><creator>Krasemann, Thomas</creator><general>Urban and Vogel</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>200903</creationdate><title>Do the Age of Patients with Tetralogy of Fallot at the Time of Surgery and the Applied Surgical Technique Influence the Reoperation Rate?</title><author>Gerling, Christoph ; Rukosujew, Andreas ; Kehl, Hans-Gerd ; Tjan, Tonny D. T. ; Hoffmeier, Andreas ; Vogt, Johannes ; Scheld, Hans-Heinrich ; Krasemann, Thomas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c166x-a7150b37a0c0b490bdfe806a733242b18f696b2b30125d86072a81ca0cefbf143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Age Distribution</topic><topic>Cardiology</topic><topic>Cardiovascular Surgical Procedures - statistics & numerical data</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Germany - epidemiology</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Internal Medicine</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Patient Selection</topic><topic>Reconstructive Surgical Procedures - statistics & numerical data</topic><topic>Reoperation</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Survival Analysis</topic><topic>Survival Rate</topic><topic>Tetralogy of Fallot - mortality</topic><topic>Tetralogy of Fallot - surgery</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gerling, Christoph</creatorcontrib><creatorcontrib>Rukosujew, Andreas</creatorcontrib><creatorcontrib>Kehl, Hans-Gerd</creatorcontrib><creatorcontrib>Tjan, Tonny D. T.</creatorcontrib><creatorcontrib>Hoffmeier, Andreas</creatorcontrib><creatorcontrib>Vogt, Johannes</creatorcontrib><creatorcontrib>Scheld, Hans-Heinrich</creatorcontrib><creatorcontrib>Krasemann, Thomas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Herz</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gerling, Christoph</au><au>Rukosujew, Andreas</au><au>Kehl, Hans-Gerd</au><au>Tjan, Tonny D. T.</au><au>Hoffmeier, Andreas</au><au>Vogt, Johannes</au><au>Scheld, Hans-Heinrich</au><au>Krasemann, Thomas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Do the Age of Patients with Tetralogy of Fallot at the Time of Surgery and the Applied Surgical Technique Influence the Reoperation Rate?: A Single-Center Experience</atitle><jtitle>Herz</jtitle><stitle>Herz</stitle><addtitle>Herz</addtitle><date>2009-03</date><risdate>2009</risdate><volume>34</volume><issue>2</issue><spage>155</spage><epage>160</epage><pages>155-160</pages><issn>0340-9937</issn><eissn>1615-6692</eissn><coden>HERZDW</coden><abstract>Background and Purpose:
Primary repair of tetralogy of Fallot (TOF) has been favored in many centers for years now and results and advantages of this management seem to verify this procedure. The authors wanted to know, if the age at the time of surgery and the surgical techniques had an influence on the long-term results.
Patients and Methods:
Between 1992 and 2003, 124 patients underwent complete repair of TOF at the University Hospital Münster, Germany. Patients were subdivided into two groups based on their age (< 1 year and > 1 year of age). Patients in whom a transannular patch (TAP) was used were compared with those without (NTAP), or in whom a conduit was used.
Results:
Overall mortality was 8%, with an average age of death of 9.53 years (range 0.06–19.77 years). The patients’ age at the time of surgery affected their survival as only two cases of death were reported among the group of children < 1 year of age (3.2%) whereas eight patients were older (12.9%; p = 0.0483). Six patients died within the first 30 days post surgery. Reoperation had to be performed in 21 cases, 13 (61.9%) of these patients were < 1 year of age at the time of surgery, eight were older (38.1%). A TAP, NTAP or conduit treatment did not show significant differences in long-term survival or freedom from reoperation.
Conclusion:
Early repair of TOF within the 1st year of life can be recommended, because mortality is lower than in patients treated at a higher age. There seems no significant difference in the reintervention rate between patients treated within the 1st year of life or later.</abstract><cop>Munchen</cop><pub>Urban and Vogel</pub><pmid>19370333</pmid><doi>10.1007/s00059-009-3169-x</doi><tpages>6</tpages></addata></record> |
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subjects | Adolescent Age Distribution Cardiology Cardiovascular Surgical Procedures - statistics & numerical data Child Child, Preschool Female Germany - epidemiology Humans Infant Infant, Newborn Internal Medicine Longitudinal Studies Male Medicine Medicine & Public Health Patient Selection Reconstructive Surgical Procedures - statistics & numerical data Reoperation Risk Assessment - methods Risk Factors Survival Analysis Survival Rate Tetralogy of Fallot - mortality Tetralogy of Fallot - surgery Treatment Outcome Young Adult |
title | Do the Age of Patients with Tetralogy of Fallot at the Time of Surgery and the Applied Surgical Technique Influence the Reoperation Rate?: A Single-Center Experience |
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