hematology of anorexia nervosa
OBJECTIVE:: Changes of the peripheral blood cell count in patients with anorexia nervosa (AN) are frequent. Anemia and leukopenia are observed in one-third of these patients. Examination of the bone marrow reveals in almost 50% of the patients with AN signs of bone marrow atrophy and can additionall...
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| Veröffentlicht in: | The International journal of eating disorders 2009-05, Vol.42 (4), p.293-300 |
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| container_title | The International journal of eating disorders |
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| creator | Hutter, Gero Ganepola, Susanne Hofmann, Wolf-K |
| description | OBJECTIVE:: Changes of the peripheral blood cell count in patients with anorexia nervosa (AN) are frequent. Anemia and leukopenia are observed in one-third of these patients. Examination of the bone marrow reveals in almost 50% of the patients with AN signs of bone marrow atrophy and can additionally suffer from a gelatinous bone marrow transformation. METHOD:: Published studies and investigations concerning hematological changes in patients with AN were reviewed. RESULTS:: Anemia and mild neutropenia are detectable in almost one-third of these patients, whereas thrombocytopenia is rather uncommon. The exact mechanism for these findings is still unclear, but 50% of AN-patients with hematological changes display morphological signs of partial bone marrow atrophy. DISCUSSION:: Changes of the peripheral blood cell count in patients with AN is a frequent observation but the peripheral blood cell count cannot predict the severity of bone marrow atrophy. All hematological and morphological alterations disappear completely and rapidly after sufficient refeeding. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2009 |
| doi_str_mv | 10.1002/eat.20610 |
| format | Article |
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Anemia and leukopenia are observed in one-third of these patients. Examination of the bone marrow reveals in almost 50% of the patients with AN signs of bone marrow atrophy and can additionally suffer from a gelatinous bone marrow transformation. METHOD:: Published studies and investigations concerning hematological changes in patients with AN were reviewed. RESULTS:: Anemia and mild neutropenia are detectable in almost one-third of these patients, whereas thrombocytopenia is rather uncommon. The exact mechanism for these findings is still unclear, but 50% of AN-patients with hematological changes display morphological signs of partial bone marrow atrophy. DISCUSSION:: Changes of the peripheral blood cell count in patients with AN is a frequent observation but the peripheral blood cell count cannot predict the severity of bone marrow atrophy. All hematological and morphological alterations disappear completely and rapidly after sufficient refeeding. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2009</description><identifier>ISSN: 0276-3478</identifier><identifier>EISSN: 1098-108X</identifier><identifier>DOI: 10.1002/eat.20610</identifier><identifier>PMID: 19040272</identifier><identifier>CODEN: INDIDJ</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult and adolescent clinical studies ; anemia (disease) ; Anemia - blood ; Anemia - epidemiology ; Anemia - etiology ; Anorexia ; Anorexia nervosa ; Anorexia Nervosa - blood ; Anorexia Nervosa - complications ; Anorexia Nervosa - pathology ; Atrophy ; Biological and medical sciences ; Blood Cell Count ; blood cell counts ; Blood diseases ; blood sampling ; body image ; bone diseases ; Bone marrow ; Bone Marrow - pathology ; bone marrow transformation ; diet-related diseases ; Eating behavior disorders ; Eating disorders ; Erythropoiesis ; Glycosaminoglycans - analysis ; GMT ; hematologic diseases ; Hematology ; Humans ; Leukocytes ; leukopenia ; Medical sciences ; neutropenia ; Neutropenia - blood ; Neutropenia - epidemiology ; Neutropenia - etiology ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; thrombocytopenia ; Thrombocytopenia - blood ; Thrombocytopenia - epidemiology ; Thrombocytopenia - etiology</subject><ispartof>The International journal of eating disorders, 2009-05, Vol.42 (4), p.293-300</ispartof><rights>Copyright © 2008 Wiley Periodicals, Inc.</rights><rights>2009 INIST-CNRS</rights><rights>Copyright Wiley Periodicals Inc. May 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5080-d5abc7fdfbcbb66e84b57e76daac13ce07d280691d57a7f7f0bdfb77d7d9e2163</citedby><cites>FETCH-LOGICAL-c5080-d5abc7fdfbcbb66e84b57e76daac13ce07d280691d57a7f7f0bdfb77d7d9e2163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Feat.20610$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Feat.20610$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21425973$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19040272$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hutter, Gero</creatorcontrib><creatorcontrib>Ganepola, Susanne</creatorcontrib><creatorcontrib>Hofmann, Wolf-K</creatorcontrib><title>hematology of anorexia nervosa</title><title>The International journal of eating disorders</title><addtitle>Int. J. Eat. Disord</addtitle><description>OBJECTIVE:: Changes of the peripheral blood cell count in patients with anorexia nervosa (AN) are frequent. Anemia and leukopenia are observed in one-third of these patients. Examination of the bone marrow reveals in almost 50% of the patients with AN signs of bone marrow atrophy and can additionally suffer from a gelatinous bone marrow transformation. METHOD:: Published studies and investigations concerning hematological changes in patients with AN were reviewed. RESULTS:: Anemia and mild neutropenia are detectable in almost one-third of these patients, whereas thrombocytopenia is rather uncommon. The exact mechanism for these findings is still unclear, but 50% of AN-patients with hematological changes display morphological signs of partial bone marrow atrophy. DISCUSSION:: Changes of the peripheral blood cell count in patients with AN is a frequent observation but the peripheral blood cell count cannot predict the severity of bone marrow atrophy. All hematological and morphological alterations disappear completely and rapidly after sufficient refeeding. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2009</description><subject>Adult and adolescent clinical studies</subject><subject>anemia (disease)</subject><subject>Anemia - blood</subject><subject>Anemia - epidemiology</subject><subject>Anemia - etiology</subject><subject>Anorexia</subject><subject>Anorexia nervosa</subject><subject>Anorexia Nervosa - blood</subject><subject>Anorexia Nervosa - complications</subject><subject>Anorexia Nervosa - pathology</subject><subject>Atrophy</subject><subject>Biological and medical sciences</subject><subject>Blood Cell Count</subject><subject>blood cell counts</subject><subject>Blood diseases</subject><subject>blood sampling</subject><subject>body image</subject><subject>bone diseases</subject><subject>Bone marrow</subject><subject>Bone Marrow - pathology</subject><subject>bone marrow transformation</subject><subject>diet-related diseases</subject><subject>Eating behavior disorders</subject><subject>Eating disorders</subject><subject>Erythropoiesis</subject><subject>Glycosaminoglycans - analysis</subject><subject>GMT</subject><subject>hematologic diseases</subject><subject>Hematology</subject><subject>Humans</subject><subject>Leukocytes</subject><subject>leukopenia</subject><subject>Medical sciences</subject><subject>neutropenia</subject><subject>Neutropenia - blood</subject><subject>Neutropenia - epidemiology</subject><subject>Neutropenia - etiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>thrombocytopenia</subject><subject>Thrombocytopenia - blood</subject><subject>Thrombocytopenia - epidemiology</subject><subject>Thrombocytopenia - etiology</subject><issn>0276-3478</issn><issn>1098-108X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10M9PFDEUB_DGaGRFD_4DuDHRxMPAe-1M38yREEAT1ARBjZfmTafFwdkptrvA_vcWZ8XExFMP_bxfXyGeI-wigNxzvNyVoBEeiBlCUxcI9deHYgaSdKFKqrfEk5QuAUArqB6LLWygzJ9yJna-uwUvwxAu1vPg5zyG6G57no8uXofET8Ujz0Nyzzbvtjg_Ojw7eFucfDx-d7B_UtgKaii6iltLvvOtbVutXV22FTnSHbNFZR1QJ2vQDXYVMXny0GZL1FHXOIlabYvXU9-rGH6uXFqaRZ-sGwYeXVglowlRk76DL_-Bl2EVx7ybkYg5DaIqozcTsjGkFJ03V7FfcFwbBHOXmMmJmd-JZbuzabhqF677KzcRZfBqAzhZHnzk0fbp3kksZdWQym5vcjf94Nb_n2gO98_-jC6mij4t3e19Bccf-V5Flfny4dio089HpyV9M--zfzF5z8HwRcxbnH-SgApQS5BQql-DJJi3</recordid><startdate>200905</startdate><enddate>200905</enddate><creator>Hutter, Gero</creator><creator>Ganepola, Susanne</creator><creator>Hofmann, Wolf-K</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><general>Wiley Subscription Services, Inc</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>200905</creationdate><title>hematology of anorexia nervosa</title><author>Hutter, Gero ; Ganepola, Susanne ; Hofmann, Wolf-K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5080-d5abc7fdfbcbb66e84b57e76daac13ce07d280691d57a7f7f0bdfb77d7d9e2163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult and adolescent clinical studies</topic><topic>anemia (disease)</topic><topic>Anemia - blood</topic><topic>Anemia - epidemiology</topic><topic>Anemia - etiology</topic><topic>Anorexia</topic><topic>Anorexia nervosa</topic><topic>Anorexia Nervosa - blood</topic><topic>Anorexia Nervosa - complications</topic><topic>Anorexia Nervosa - pathology</topic><topic>Atrophy</topic><topic>Biological and medical sciences</topic><topic>Blood Cell Count</topic><topic>blood cell counts</topic><topic>Blood diseases</topic><topic>blood sampling</topic><topic>body image</topic><topic>bone diseases</topic><topic>Bone marrow</topic><topic>Bone Marrow - pathology</topic><topic>bone marrow transformation</topic><topic>diet-related diseases</topic><topic>Eating behavior disorders</topic><topic>Eating disorders</topic><topic>Erythropoiesis</topic><topic>Glycosaminoglycans - analysis</topic><topic>GMT</topic><topic>hematologic diseases</topic><topic>Hematology</topic><topic>Humans</topic><topic>Leukocytes</topic><topic>leukopenia</topic><topic>Medical sciences</topic><topic>neutropenia</topic><topic>Neutropenia - blood</topic><topic>Neutropenia - epidemiology</topic><topic>Neutropenia - etiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>thrombocytopenia</topic><topic>Thrombocytopenia - blood</topic><topic>Thrombocytopenia - epidemiology</topic><topic>Thrombocytopenia - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hutter, Gero</creatorcontrib><creatorcontrib>Ganepola, Susanne</creatorcontrib><creatorcontrib>Hofmann, Wolf-K</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The International journal of eating disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hutter, Gero</au><au>Ganepola, Susanne</au><au>Hofmann, Wolf-K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>hematology of anorexia nervosa</atitle><jtitle>The International journal of eating disorders</jtitle><addtitle>Int. 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The exact mechanism for these findings is still unclear, but 50% of AN-patients with hematological changes display morphological signs of partial bone marrow atrophy. DISCUSSION:: Changes of the peripheral blood cell count in patients with AN is a frequent observation but the peripheral blood cell count cannot predict the severity of bone marrow atrophy. All hematological and morphological alterations disappear completely and rapidly after sufficient refeeding. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2009</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>19040272</pmid><doi>10.1002/eat.20610</doi><tpages>8</tpages></addata></record> |
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| subjects | Adult and adolescent clinical studies anemia (disease) Anemia - blood Anemia - epidemiology Anemia - etiology Anorexia Anorexia nervosa Anorexia Nervosa - blood Anorexia Nervosa - complications Anorexia Nervosa - pathology Atrophy Biological and medical sciences Blood Cell Count blood cell counts Blood diseases blood sampling body image bone diseases Bone marrow Bone Marrow - pathology bone marrow transformation diet-related diseases Eating behavior disorders Eating disorders Erythropoiesis Glycosaminoglycans - analysis GMT hematologic diseases Hematology Humans Leukocytes leukopenia Medical sciences neutropenia Neutropenia - blood Neutropenia - epidemiology Neutropenia - etiology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry thrombocytopenia Thrombocytopenia - blood Thrombocytopenia - epidemiology Thrombocytopenia - etiology |
| title | hematology of anorexia nervosa |
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