Decreased Immune Activation in Resistance to HIV-1 Infection Is Associated with an Elevated Frequency of CD4+CD25+FOXP3+ Regulatory T Cells

Human immunodeficiency virus (HIV)–resistant commercial sex workers provide a unique opportunity to study correlates of protection associated with natural resistance to HIV infection. Emerging data from studies of these individuals and other uninfected individuals who have been exposed to HIV sugges...

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Veröffentlicht in:	The Journal of infectious diseases 2009-05, Vol.199 (9), p.1318-1322
Hauptverfasser:	Card, Catherine M., McLaren, Paul J., Wachihi, Charles, Kimani, Joshua, Plummer, Francis A., Fowke, Keith R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - immunology ADP-ribosyl Cyclase 1 - analysis AIDS Antigens, CD - immunology Biological and medical sciences CD4 Antigens - immunology CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Commercial regulation Female Forkhead Transcription Factors - immunology Fundamental and applied biological sciences. Psychology HIV HIV 1 HIV infections HIV Infections - blood HIV Infections - immunology HIV Seronegativity - immunology HIV-1 - genetics HIV-1 - immunology HIV/AIDS HLA-DR Antigens - analysis Human viral diseases Humans Immunity, Innate Infections Infectious diseases Interleukin-2 Receptor alpha Subunit - immunology Kenya Lymphocyte Activation Medical sciences Microbiology Miscellaneous Polymerase Chain Reaction Sex Work - statistics & numerical data Sex workers T lymphocytes T-Lymphocytes, Regulatory - immunology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology Viruses
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