Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells

Insulin-like growth factor 1 (IGF1) is involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly. The present study aimed to determine whether IGFBP3 is i...

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Veröffentlicht in:	Zoological Science 2009-02, Vol.26 (2), p.131-138
Hauptverfasser:	Maekawa, Tetsuya, Takeuchi, Sakae, Kanayama, Munetoshi, Takahashi, Sumio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western DNA - biosynthesis Endometrium - cytology Endometrium - drug effects Endometrium - metabolism Enzyme Inhibitors - pharmacology Epithelial Cells - drug effects Epithelial Cells - metabolism Estradiol - pharmacology estrogen Female IGF1 IGFBP3 Insulin-Like Growth Factor Binding Protein 3 - antagonists & inhibitors Insulin-Like Growth Factor Binding Protein 3 - biosynthesis Insulin-Like Growth Factor Binding Protein 3 - genetics Insulin-Like Growth Factor I - biosynthesis Insulin-Like Growth Factor I - genetics Mice Mice, Inbred ICR mouse ORIGINAL ARTICLES Progesterone - pharmacology Quinazolines Receptor, IGF Type 1 - biosynthesis Receptor, IGF Type 1 - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis RNA, Messenger - genetics Stromal Cells - drug effects Stromal Cells - metabolism Transforming Growth Factor alpha - antagonists & inhibitors Transforming Growth Factor alpha - pharmacology Tyrphostins - pharmacology uterus
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