Prospective, Randomized Trial of 10 Days versus 30 Days of Antimicrobial Treatment, Including a Short-Term Course of Parenteral Therapy, for Childhood Septic Arthritis

Background. The standard treatment for septic arthritis in children is antimicrobials for several weeks (initially administered intravenously) and arthrotomy (at least for the hip and shoulder joints). No sufficiently powered study has examined the true need for these treatments. Methods. In a rando...

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Veröffentlicht in:	Clinical infectious diseases 2009-05, Vol.48 (9), p.1201-121
Hauptverfasser:	Peltola, Heikki, Pääkkönen, Markus, Kallio, Pentti, Kallio, Markku J. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Antibiotics Antimicrobial agents Antimicrobials Arthritis Arthritis, Infectious - drug therapy Articles and Commentaries Biological and medical sciences Bones C-Reactive Protein - analysis Cephalosporins - administration & dosage Cephalosporins - therapeutic use Child Child, Preschool Childhood Children Children & youth Clindamycin - administration & dosage Clindamycin - therapeutic use Diseases of the osteoarticular system Erythrocyte sedimentation rate Female Finland Haemophilus influenzae Haemophilus influenzae - isolation & purification Humans Infant Infections Infectious diseases Joints Male Medical research Medical sciences Miscellaneous. Osteoarticular involvement in other diseases Osteomyelitis Parenteral nutrition Prospective Studies Sepsis Staphylococcus aureus Staphylococcus aureus - isolation & purification Streptococcus pyogenes Streptococcus pyogenes - isolation & purification Surgical procedures Time Factors Treatment Outcome
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