2-deoxy-2-[ 18F] fluoro-D-glucose uptake in intercostal respiratory muscles on positron emission tomography/computed tomography: smokers versus nonsmokers
The purpose of this study was to determine the frequency of 2-deoxy-2-[ 18F]fluoro-D-glucose (FDG) uptake in the intercostal respiratory muscles (ICM) of smokers versus nonsmokers using positron emission tomography (PET). Ninety-six whole-body PET/computed tomography (CT) scans were retrospectively...
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| Veröffentlicht in: | Molecular imaging and biology 2004-11, Vol.6 (6), p.405-410 |
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| creator | Jacene, Heather A. Patel, Pavni P. Chin, Bennett B. |
| description | The purpose of this study was to determine the frequency of 2-deoxy-2-[
18F]fluoro-D-glucose (FDG) uptake in the intercostal respiratory muscles (ICM) of smokers versus nonsmokers using positron emission tomography (PET).
Ninety-six whole-body PET/computed tomography (CT) scans were retrospectively reviewed; 61 studies were from smokers and 35 from nonsmokers. The ICM uptake from the lung apices to the level of the carina was visually scored with respect to FDG intensity as follows: 0
=
uptake less than or equal to lung uptake; 1
=
greater than lung, but less than mediastinal blood pool; 2
=
equal to mediastinal blood pool; and 3
=
greater than mediastinal blood pool.
In smokers, 30 out of 61 (49.2%) PET/CT scans had uptake that localized to ICM, compared to 3/35 (8.6%) studies in nonsmokers. Average ICM uptake was significantly different between smokers and nonsmokers (0.787 ± 0.933 and 0.143 ± 0.494, respectively;
P < 0.01).
Increased FDG uptake in ICM is a physiologic pattern of uptake that is frequently seen and is more common in smokers. |
| doi_str_mv | 10.1016/j.mibio.2004.08.002 |
| format | Article |
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18F]fluoro-D-glucose (FDG) uptake in the intercostal respiratory muscles (ICM) of smokers versus nonsmokers using positron emission tomography (PET).
Ninety-six whole-body PET/computed tomography (CT) scans were retrospectively reviewed; 61 studies were from smokers and 35 from nonsmokers. The ICM uptake from the lung apices to the level of the carina was visually scored with respect to FDG intensity as follows: 0
=
uptake less than or equal to lung uptake; 1
=
greater than lung, but less than mediastinal blood pool; 2
=
equal to mediastinal blood pool; and 3
=
greater than mediastinal blood pool.
In smokers, 30 out of 61 (49.2%) PET/CT scans had uptake that localized to ICM, compared to 3/35 (8.6%) studies in nonsmokers. Average ICM uptake was significantly different between smokers and nonsmokers (0.787 ± 0.933 and 0.143 ± 0.494, respectively;
P < 0.01).
Increased FDG uptake in ICM is a physiologic pattern of uptake that is frequently seen and is more common in smokers.</description><identifier>ISSN: 1536-1632</identifier><identifier>EISSN: 1860-2002</identifier><identifier>DOI: 10.1016/j.mibio.2004.08.002</identifier><identifier>PMID: 15564151</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>2-deoxy-2-[ 18F] fluoro-D-glucose ; Adult ; Aged ; Aged, 80 and over ; FDG ; Female ; Fluorodeoxyglucose F18 - metabolism ; Fluorodeoxyglucose F18 - pharmacokinetics ; Humans ; Intercostal Muscles - diagnostic imaging ; Intercostal Muscles - metabolism ; Intercostal Respiratory Muscles ; Male ; Middle Aged ; PET ; PET/CT ; Positron Emission Tomography ; Retrospective Studies ; Smokers ; Smoking - physiopathology ; Tomography, X-Ray Computed</subject><ispartof>Molecular imaging and biology, 2004-11, Vol.6 (6), p.405-410</ispartof><rights>2004 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-9bb931ab13acd07c27e036cb4fb1d6dc6ae722633061b3586b90747532a8864a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15564151$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jacene, Heather A.</creatorcontrib><creatorcontrib>Patel, Pavni P.</creatorcontrib><creatorcontrib>Chin, Bennett B.</creatorcontrib><title>2-deoxy-2-[ 18F] fluoro-D-glucose uptake in intercostal respiratory muscles on positron emission tomography/computed tomography: smokers versus nonsmokers</title><title>Molecular imaging and biology</title><addtitle>Mol Imaging Biol</addtitle><description>The purpose of this study was to determine the frequency of 2-deoxy-2-[
18F]fluoro-D-glucose (FDG) uptake in the intercostal respiratory muscles (ICM) of smokers versus nonsmokers using positron emission tomography (PET).
Ninety-six whole-body PET/computed tomography (CT) scans were retrospectively reviewed; 61 studies were from smokers and 35 from nonsmokers. The ICM uptake from the lung apices to the level of the carina was visually scored with respect to FDG intensity as follows: 0
=
uptake less than or equal to lung uptake; 1
=
greater than lung, but less than mediastinal blood pool; 2
=
equal to mediastinal blood pool; and 3
=
greater than mediastinal blood pool.
In smokers, 30 out of 61 (49.2%) PET/CT scans had uptake that localized to ICM, compared to 3/35 (8.6%) studies in nonsmokers. Average ICM uptake was significantly different between smokers and nonsmokers (0.787 ± 0.933 and 0.143 ± 0.494, respectively;
P < 0.01).
Increased FDG uptake in ICM is a physiologic pattern of uptake that is frequently seen and is more common in smokers.</description><subject>2-deoxy-2-[ 18F] fluoro-D-glucose</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>FDG</subject><subject>Female</subject><subject>Fluorodeoxyglucose F18 - metabolism</subject><subject>Fluorodeoxyglucose F18 - pharmacokinetics</subject><subject>Humans</subject><subject>Intercostal Muscles - diagnostic imaging</subject><subject>Intercostal Muscles - metabolism</subject><subject>Intercostal Respiratory Muscles</subject><subject>Male</subject><subject>Middle Aged</subject><subject>PET</subject><subject>PET/CT</subject><subject>Positron Emission Tomography</subject><subject>Retrospective Studies</subject><subject>Smokers</subject><subject>Smoking - physiopathology</subject><subject>Tomography, X-Ray Computed</subject><issn>1536-1632</issn><issn>1860-2002</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc2KFDEUhYMozo8-gSBZuUvNTVKVqhZcyOiMwoAbXYmEJHV7TE9VpczPYL-KT2vGbtCVEJLD4dx7k3yEvODQcODqYtfM3vrQCIC2gaEBEI_IKR8UsGqJx1V3UjGupDghZyntAHjPhXxKTnjXqZZ3_JT8EmzE8HPPBPtK-XD1jW6nEmJg79jtVFxISMuazR1Sv9SVMVYvm4lGTKuPJoe4p3NJbsJEw0LXkHyOVeDsU_JV5DCH22jW7_sLF-a1ZBz_8V7TNIc7jIne160kuoTl6DwjT7ZmSvj8eJ6TL1fvP19-YDefrj9evr1hTnZ9ZhtrN5Iby6VxI_RO9AhSOdtuLR_V6JTBXgglJShuZTcou4G-7TspzDCo1shz8urQd43hR8GUdb26w2kyC4aStOo51H-DGpSHoIshpYhbvUY_m7jXHPQDEr3Tf5DoByQaBl0x1KqXx_bFzjj-rTkyqIE3hwDWR957jDo5j4vD0Ud0WY_B_3fAb-K3oYg</recordid><startdate>20041101</startdate><enddate>20041101</enddate><creator>Jacene, Heather A.</creator><creator>Patel, Pavni P.</creator><creator>Chin, Bennett B.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20041101</creationdate><title>2-deoxy-2-[ 18F] fluoro-D-glucose uptake in intercostal respiratory muscles on positron emission tomography/computed tomography: smokers versus nonsmokers</title><author>Jacene, Heather A. ; Patel, Pavni P. ; Chin, Bennett B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-9bb931ab13acd07c27e036cb4fb1d6dc6ae722633061b3586b90747532a8864a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>2-deoxy-2-[ 18F] fluoro-D-glucose</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>FDG</topic><topic>Female</topic><topic>Fluorodeoxyglucose F18 - metabolism</topic><topic>Fluorodeoxyglucose F18 - pharmacokinetics</topic><topic>Humans</topic><topic>Intercostal Muscles - diagnostic imaging</topic><topic>Intercostal Muscles - metabolism</topic><topic>Intercostal Respiratory Muscles</topic><topic>Male</topic><topic>Middle Aged</topic><topic>PET</topic><topic>PET/CT</topic><topic>Positron Emission Tomography</topic><topic>Retrospective Studies</topic><topic>Smokers</topic><topic>Smoking - physiopathology</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jacene, Heather A.</creatorcontrib><creatorcontrib>Patel, Pavni P.</creatorcontrib><creatorcontrib>Chin, Bennett B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular imaging and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jacene, Heather A.</au><au>Patel, Pavni P.</au><au>Chin, Bennett B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>2-deoxy-2-[ 18F] fluoro-D-glucose uptake in intercostal respiratory muscles on positron emission tomography/computed tomography: smokers versus nonsmokers</atitle><jtitle>Molecular imaging and biology</jtitle><addtitle>Mol Imaging Biol</addtitle><date>2004-11-01</date><risdate>2004</risdate><volume>6</volume><issue>6</issue><spage>405</spage><epage>410</epage><pages>405-410</pages><issn>1536-1632</issn><eissn>1860-2002</eissn><abstract>The purpose of this study was to determine the frequency of 2-deoxy-2-[
18F]fluoro-D-glucose (FDG) uptake in the intercostal respiratory muscles (ICM) of smokers versus nonsmokers using positron emission tomography (PET).
Ninety-six whole-body PET/computed tomography (CT) scans were retrospectively reviewed; 61 studies were from smokers and 35 from nonsmokers. The ICM uptake from the lung apices to the level of the carina was visually scored with respect to FDG intensity as follows: 0
=
uptake less than or equal to lung uptake; 1
=
greater than lung, but less than mediastinal blood pool; 2
=
equal to mediastinal blood pool; and 3
=
greater than mediastinal blood pool.
In smokers, 30 out of 61 (49.2%) PET/CT scans had uptake that localized to ICM, compared to 3/35 (8.6%) studies in nonsmokers. Average ICM uptake was significantly different between smokers and nonsmokers (0.787 ± 0.933 and 0.143 ± 0.494, respectively;
P < 0.01).
Increased FDG uptake in ICM is a physiologic pattern of uptake that is frequently seen and is more common in smokers.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>15564151</pmid><doi>10.1016/j.mibio.2004.08.002</doi><tpages>6</tpages></addata></record> |
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| ispartof | Molecular imaging and biology, 2004-11, Vol.6 (6), p.405-410 |
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| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | 2-deoxy-2-[ 18F] fluoro-D-glucose Adult Aged Aged, 80 and over FDG Female Fluorodeoxyglucose F18 - metabolism Fluorodeoxyglucose F18 - pharmacokinetics Humans Intercostal Muscles - diagnostic imaging Intercostal Muscles - metabolism Intercostal Respiratory Muscles Male Middle Aged PET PET/CT Positron Emission Tomography Retrospective Studies Smokers Smoking - physiopathology Tomography, X-Ray Computed |
| title | 2-deoxy-2-[ 18F] fluoro-D-glucose uptake in intercostal respiratory muscles on positron emission tomography/computed tomography: smokers versus nonsmokers |
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