Portal vein arterialization for liver transplantation with extensive portomesenteric vein thrombosis: A case report
We report herein a case of extensive thrombosis of portal venous system including mesenteric vein in a 70-year-old man who suffered from end-stage post–hepatitis C cirrhosis and who underwent orthotopic liver transplantation. There was no way to divert portal blood flow to the new liver because such...
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Veröffentlicht in: | Transplantation proceedings 2004-10, Vol.36 (8), p.2267-2268 |
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description | We report herein a case of extensive thrombosis of portal venous system including mesenteric vein in a 70-year-old man who suffered from end-stage post–hepatitis C cirrhosis and who underwent orthotopic liver transplantation. There was no way to divert portal blood flow to the new liver because such an extensive thrombosis of portomesenteric venous system. There are some case reports of portocaval hemitransposition with some success but high mortality. We decided to arterialize the portal vein of the liver allograft with the recipient hepatic artery and the donor hepatic artery was anastomosed to the supraceliac aorta. He recovered slowly from the operation. At 1 year after the transplantation, he is doing well with perfect liver function tests. This case challenges our belief that portal blood flow is essential for the liver because of hepatotrophic factors. |
doi_str_mv | 10.1016/j.transproceed.2004.07.073 |
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There was no way to divert portal blood flow to the new liver because such an extensive thrombosis of portomesenteric venous system. There are some case reports of portocaval hemitransposition with some success but high mortality. We decided to arterialize the portal vein of the liver allograft with the recipient hepatic artery and the donor hepatic artery was anastomosed to the supraceliac aorta. He recovered slowly from the operation. At 1 year after the transplantation, he is doing well with perfect liver function tests. This case challenges our belief that portal blood flow is essential for the liver because of hepatotrophic factors.</description><identifier>ISSN: 0041-1345</identifier><identifier>EISSN: 1873-2623</identifier><identifier>DOI: 10.1016/j.transproceed.2004.07.073</identifier><identifier>PMID: 15561214</identifier><identifier>CODEN: TRPPA8</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Hepatic Artery - physiology ; Hepatic Veins - surgery ; Humans ; Liver Transplantation - methods ; Male ; Medical sciences ; Portal Vein - surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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There was no way to divert portal blood flow to the new liver because such an extensive thrombosis of portomesenteric venous system. There are some case reports of portocaval hemitransposition with some success but high mortality. We decided to arterialize the portal vein of the liver allograft with the recipient hepatic artery and the donor hepatic artery was anastomosed to the supraceliac aorta. He recovered slowly from the operation. At 1 year after the transplantation, he is doing well with perfect liver function tests. This case challenges our belief that portal blood flow is essential for the liver because of hepatotrophic factors.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Hepatic Artery - physiology</subject><subject>Hepatic Veins - surgery</subject><subject>Humans</subject><subject>Liver Transplantation - methods</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Portal Vein - surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Vascular system</topic><topic>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Hepatic Artery - physiology</topic><topic>Hepatic Veins - surgery</topic><topic>Humans</topic><topic>Liver Transplantation - methods</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Portal Vein - surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Tissue, organ and graft immunology</topic><topic>Venous Thrombosis - complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nivatvongs, S.</creatorcontrib><creatorcontrib>Sirijindakul, B.</creatorcontrib><creatorcontrib>Nontasoot, B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transplantation proceedings</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nivatvongs, S.</au><au>Sirijindakul, B.</au><au>Nontasoot, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Portal vein arterialization for liver transplantation with extensive portomesenteric vein thrombosis: A case report</atitle><jtitle>Transplantation proceedings</jtitle><addtitle>Transplant Proc</addtitle><date>2004-10-01</date><risdate>2004</risdate><volume>36</volume><issue>8</issue><spage>2267</spage><epage>2268</epage><pages>2267-2268</pages><issn>0041-1345</issn><eissn>1873-2623</eissn><coden>TRPPA8</coden><abstract>We report herein a case of extensive thrombosis of portal venous system including mesenteric vein in a 70-year-old man who suffered from end-stage post–hepatitis C cirrhosis and who underwent orthotopic liver transplantation. There was no way to divert portal blood flow to the new liver because such an extensive thrombosis of portomesenteric venous system. There are some case reports of portocaval hemitransposition with some success but high mortality. We decided to arterialize the portal vein of the liver allograft with the recipient hepatic artery and the donor hepatic artery was anastomosed to the supraceliac aorta. He recovered slowly from the operation. At 1 year after the transplantation, he is doing well with perfect liver function tests. This case challenges our belief that portal blood flow is essential for the liver because of hepatotrophic factors.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>15561214</pmid><doi>10.1016/j.transproceed.2004.07.073</doi><tpages>2</tpages></addata></record> |
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subjects | Aged Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Fundamental and applied biological sciences. Psychology Fundamental immunology Hepatic Artery - physiology Hepatic Veins - surgery Humans Liver Transplantation - methods Male Medical sciences Portal Vein - surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Venous Thrombosis - complications |
title | Portal vein arterialization for liver transplantation with extensive portomesenteric vein thrombosis: A case report |
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