TRAIL induction by radiation in lymphoma patients

TRAIL/Apo-2 L, a member of the Tumor Necrosis Factor cytokine family, induces apoptosis specifically in malignant cells. A combination of TRAIL and radiation is highly synergistic in in vitro experiments. In addition to this additive effect, we observed that TRAIL is induced by irradiation of certai...

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Veröffentlicht in:	Cancer investigation 2004, Vol.22 (4), p.522-525
Hauptverfasser:	Unnithan, Jaya, Macklis, Roger M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Apoptosis Regulatory Proteins Hodgkin Disease - metabolism Hodgkin Disease - radiotherapy Humans Lymphoma, Non-Hodgkin - metabolism Lymphoma, Non-Hodgkin - radiotherapy Male Membrane Glycoproteins - metabolism Middle Aged TNF-Related Apoptosis-Inducing Ligand Treatment Outcome Tumor Necrosis Factor-alpha - metabolism
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