Detection of fascin and CCR-7 positive mature dendritic cells in oral lichen planus

Background: Dendritic cells (DC) play a crucial role in the pathogenesis of oral lichen planus (OLP) with respect to antigens presented to T cells. We performed immunohistochemical analysis to elucidate the process of activation of DC in OLP. Methods: Thirty biopsy specimens were obtained from the...

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Veröffentlicht in:	Journal of oral pathology & medicine 2009-04, Vol.38 (4), p.334-342
Hauptverfasser:	Mukae, Shotaro, Okazaki, Yasuhiro, Tsuda, Hirotaka, Nagai, Koichi, Matsumoto, Naoyuki, Ochiai, Toyoko, Oki, Hidero, Komiyama, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens, CD - analysis Biological and medical sciences Carrier Proteins - analysis Carrier Proteins - biosynthesis chemokine receptor-7 Cyclooxygenase 2 - biosynthesis Dendritic Cells - chemistry Dendritic Cells - immunology Dendritic Cells - pathology Dentistry Dermatology Dinoprostone - analysis Dinoprostone - biosynthesis Epithelium - pathology fascin Female Humans Immunohistochemistry Intramolecular Oxidoreductases - biosynthesis Langerhans cell Langerin Lectins, C-Type - analysis Lichen Planus, Oral - immunology Lichen Planus, Oral - metabolism Lichen Planus, Oral - pathology Lymphatic Vessels - pathology Male Mannose-Binding Lectins - analysis Medical sciences Microfilament Proteins - analysis Microfilament Proteins - biosynthesis Middle Aged Mouth Mucosa - pathology oral lichen planus Otorhinolaryngology. Stomatology Prostaglandin-E Synthases Psoriasis. Parapsoriasis. Lichen Receptors, CCR7 - analysis Receptors, CCR7 - biosynthesis Retrospective Studies Young Adult
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