Platelet-Activating Factor and Kinin-Dependent Vascular Leakage as a Novel Functional Activity of the Soluble Terminal Complement Complex

The infrequent occurrence of septic shock in patients with inherited deficiencies of the terminal complement components experiencing meningococcal disease led us to suspect that the terminal complement complex is involved in vascular leakage. To this end, the permeabilizing effect of the cytolytical...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 2004-12, Vol.173 (11), p.6921-6927
Hauptverfasser:	Bossi, Fleur, Fischetti, Fabio, Pellis, Valentina, Bulla, Roberta, Ferrero, Elisabetta, Mollnes, Tom Eirik, Regoli, Domenico, Tedesco, Francesco
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bradykinin - pharmacology Bradykinin - physiology Capillary Permeability - drug effects Capillary Permeability - immunology Cell Line Complement Membrane Attack Complex - administration & dosage Complement Membrane Attack Complex - pharmacology Complement Membrane Attack Complex - physiology Cytotoxicity, Immunologic - drug effects Dose-Response Relationship, Immunologic Endothelium, Vascular - cytology Endothelium, Vascular - drug effects Endothelium, Vascular - immunology Endothelium, Vascular - metabolism Fluorescein-5-isothiocyanate - administration & dosage Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescein-5-isothiocyanate - pharmacology Humans Ileum - blood supply Ileum - immunology Ileum - ultrastructure Intercellular Junctions - drug effects Intercellular Junctions - immunology Male Mesentery - blood supply Mesentery - immunology Mesentery - ultrastructure Perfusion Platelet Activating Factor - physiology Rats Rats, Inbred WKY Serum Albumin, Bovine - administration & dosage Serum Albumin, Bovine - pharmacology Solubility
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!