Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample

Objective: This study examined the association between the Apolipoprotein-E ε4 allele (APOE ε4) and age of disease onset in a bi-ethnic sample of community dwelling Alzheimer's disease (AD) patients. Design: Cross-sectional study of AD patients evaluated at a University-affiliated outpatient me...

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Veröffentlicht in:	International psychogeriatrics 2004-09, Vol.16 (3), p.317-326
Hauptverfasser:	Harwood, Dylan G., Barker, Warren W., Ownby, Raymond L., George-Hyslop, Peter St, Mullan, Michael, Duara, Ranjan
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age of Onset Aged Alleles Alzheimer Disease - ethnology Alzheimer Disease - genetics Alzheimer's disease Apolipoproteins Apolipoproteins E - genetics Biological and medical sciences Cross-Sectional Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Ethnic Groups - psychology Ethnic Groups - statistics & numerical data Female Gene Frequency - genetics Genotype Humans Male Medical sciences Neurology Polymorphism, Genetic - genetics
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