Interferon beta-1b in secondary progressive MS: A combined analysis of the two trials

A European (EU) and a North American (NA) placebo-controlled study with interferon beta-1b (IFNB-1b) in secondary progressive multiple sclerosis (SPMS) showed divergent results with regard to their primary outcome of sustained Expanded Disability Status Scale (EDSS) progression, while effects were s...

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Veröffentlicht in:	Neurology 2004-11, Vol.63 (10), p.1779-1787
Hauptverfasser:	KAPPOS, L, WEINSHENKER, B, POZZILLI, C, THOMPSON, A. J, DAHLKE, F, BECKMANN, K, POLMAN, C, MCFARLAND, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Brain - pathology Disability Evaluation Disease Progression Female Humans Immunologic Factors - therapeutic use Immunomodulators Interferon beta-1b Interferon-beta - therapeutic use Magnetic Resonance Imaging Male Medical sciences Middle Aged Multicenter Studies as Topic Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Multiple Sclerosis, Chronic Progressive - drug therapy Multiple Sclerosis, Chronic Progressive - pathology Neurology Outcome Assessment, Health Care - methods Patient Selection Pharmacology. Drug treatments Randomized Controlled Trials as Topic - methods Recurrence Retrospective Studies Severity of Illness Index Treatment Outcome
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