Famotidine Orally Disintegrating Tablets: Bitterness Comparison of Original and Generic Products

The purpose of the present study was to compare the palatability of the original and eight generic versions of famotidine orally disintegrating tablets by means of human gustatory sensation tests, a comparison of the release profiles, and using an automated taste sensor, the α-Astree Electronic Tong...

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Veröffentlicht in:	Chemical & Pharmaceutical Bulletin 2009/04/01, Vol.57(4), pp.382-387
Hauptverfasser:	Tokuyama, Emi, Matsunaga, Chiharu, Yoshida, Koichi, Mifsud, Jean-Christophe, Irie, Tetsumi, Yoshida, Miyako, Uchida, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Aspartame - chemistry bitterness Drugs, Generic Euclidean distance Famotidine - administration & dosage Famotidine - chemistry famotidine orally disintegrating tablet generic product Histamine H2 Antagonists - administration & dosage Histamine H2 Antagonists - chemistry Humans Principal Component Analysis Quinine - chemistry Solubility Sweetening Agents - chemistry Taste taste sensor
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