Differences in gene expression between B-cell chronic lymphocytic leukemia and normal B cells: a meta-analysis of three microarray studies

Motivation: A major focus of current cancer research is to identify genes that can be used as markers for prognosis and diagnosis, and as targets for therapy. Microarray technology has been applied extensively for this purpose, even though it has been reported that the agreement between microarray p...

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Veröffentlicht in:	Bioinformatics 2004-11, Vol.20 (17), p.3166-3178
Hauptverfasser:	Wang, J., Coombes, K. R., Highsmith, W. E., Keating, M. J., Abruzzo, L. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Biomarkers, Tumor - classification Biomarkers, Tumor - genetics Fundamental and applied biological sciences. Psychology Gene Expression Profiling - methods General aspects Genetic Variation Humans Leukemia, Lymphocytic, Chronic, B-Cell - classification Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - metabolism Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Neoplasm Proteins - classification Neoplasm Proteins - genetics Oligonucleotide Array Sequence Analysis Reference Values Reproducibility of Results Sensitivity and Specificity Sequence Analysis, DNA - methods Software
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