Low-power laser irradiation promotes cell proliferation by activating PI3K/Akt pathway

Low‐power laser irradiation (LPLI) can stimulate cell proliferation through a wide network of signals. Akt is an important protein kinase in modulating cell proliferation. In this study, using real‐time single‐cell analysis, we investigated the activity of Akt and its effects on cell proliferation i...

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Veröffentlicht in:	Journal of cellular physiology 2009-06, Vol.219 (3), p.553-562
Hauptverfasser:	Zhang, Lingling, Xing, Da, Gao, Xuejuan, Wu, Shengnan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carbazoles - pharmacology Cell Proliferation - drug effects Cell Proliferation - radiation effects Cell Survival - radiation effects Cercopithecus aethiops COS Cells Enzyme Activation - radiation effects Fluorescence Resonance Energy Transfer Indoles Lasers Maleimides Models, Biological Phosphatidylinositol 3-Kinases - antagonists & inhibitors Phosphatidylinositol 3-Kinases - metabolism Protein Kinase Inhibitors - pharmacology Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism Pyrazoles - pharmacology Pyrimidines - pharmacology Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Signal Transduction - drug effects Signal Transduction - radiation effects src-Family Kinases - antagonists & inhibitors Transfection
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