Cell surface biology mediated by low affinity multivalent protein–glycan interactions

Glycan-binding proteins mediate diverse aspects of cell biology including pathogen recognition of host cells, cell trafficking, endocytosis and modulation of cell signaling. This is accomplished despite the intrinsic low affinity for their ligands through multivalent interactions that increase effec...

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Veröffentlicht in:	Current opinion in chemical biology 2004-12, Vol.8 (6), p.617-625
Hauptverfasser:	Collins, Brian E, Paulson, James C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Proteins - metabolism Cell Adhesion Cell Communication Cell Movement Ligands Polysaccharides - metabolism Protein Binding Receptors, Cell Surface - metabolism Viral Proteins - metabolism
Online-Zugang:	Volltext
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