The cell-penetrating peptide octa-arginine is a potent inhibitor of proteasome activities

Oligo-arginines are cell-penetrating peptides and find use as carriers for transportation of various membrane-impermeable biopharmaceuticals into target cells. We have found that oligo-arginines of a length of 4–10 amino acids, but especially (Arg) 8, are able to inhibit the major intracellular prot...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European journal of pharmaceutics and biopharmaceutics 2009-05, Vol.72 (1), p.219-225
Hauptverfasser: Kloß, Alexander, Henklein, Peter, Siele, Dagmar, Schmolke, Marion, Apcher, Sébastien, Kuehn, Lothar, Sheppard, Paul W., Dahlmann, Burkhardt
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!