BRAK/CXCL14 is a potent inhibitor of angiogenesis and a chemotactic factor for immature dendritic cells

BRAK/CXCL14 is a CXC chemokine constitutively expressed at the mRNA level in certain normal tissues but absent from many established tumor cell lines and human cancers. Although multiple investigators cloned BRAK, little is known regarding the physiologic function of BRAK or the reason for decreased...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2004-11, Vol.64 (22), p.8262-8270
Hauptverfasser:	SHELLENBERGER, Thomas D, WANG, Mary, CLAYMAN, Gary L, FREDERICK, Mitchell J, GUJRATI, Manu, JAYAKUMAR, Arumugam, STRIETER, Robert M, BURDICK, Marie D, IOANNIDES, Constantin G, EFFERSON, Clayton L, EL-NAGGAR, Adel K, ROBERTS, Dianna
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Carcinoma, Squamous Cell - blood supply Carcinoma, Squamous Cell - metabolism Cell Line Chemokines, CXC - genetics Chemokines, CXC - metabolism Chemokines, CXC - physiology Chemotactic Factors - physiology Cornea - blood supply Dendritic Cells - cytology Fibroblast Growth Factor 2 - physiology Humans Interleukin-8 - physiology Medical sciences Neovascularization, Pathologic Pharmacology. Drug treatments Recombinant Proteins - genetics Recombinant Proteins - metabolism RNA, Messenger - genetics Tongue Neoplasms - blood supply Tongue Neoplasms - metabolism Vascular Endothelial Growth Factor A - physiology
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