Identification of a new HIV Type 1 Circulating Recombinant Form (CRF38_BF1) in Uruguay
Recombination has been shown to be an important force in HIV-1 evolution. Recombination contributes to an increase in genetic variation and hinders vaccine design efforts. Several molecular epidemiology studies in South America described the circulation of subtypes B, F, and C as well as several B/F...
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| Veröffentlicht in: | AIDS research and human retroviruses 2009-03, Vol.25 (3), p.351-356 |
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| container_start_page | 351 |
| container_title | AIDS research and human retroviruses |
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| creator | RUCHANSKY, Dora CASADO, Concepcion RUSSI, José C ARBIZA, Juan R LOPEZ-GALINDEZ, Cecilio |
| description | Recombination has been shown to be an important force in HIV-1 evolution. Recombination contributes to an increase in genetic variation and hinders vaccine design efforts. Several molecular epidemiology studies in South America described the circulation of subtypes B, F, and C as well as several B/F1 recombinants. This study performed by nucleotide sequencing in at least two genes of 89 samples from Uruguay has shown a complex HIV-1 epidemic characterized by the cocirculation of subtype B, and subtype C strains, together with an important group of BF1 recombinant viruses, including isolates similar to CRF12_BF. In addition we identified a new circulating recombinant form, designated CRF38_BF(1), which was dominant in the recombinant virus group. |
| doi_str_mv | 10.1089/aid.2008.0248 |
| format | Article |
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In addition we identified a new circulating recombinant form, designated CRF38_BF(1), which was dominant in the recombinant virus group.</description><identifier>ISSN: 0889-2229</identifier><identifier>EISSN: 1931-8405</identifier><identifier>DOI: 10.1089/aid.2008.0248</identifier><identifier>PMID: 19327055</identifier><identifier>CODEN: ARHRE7</identifier><language>eng</language><publisher>New Rochelle, NY: Liebert</publisher><subject>AIDS/HIV ; Biological and medical sciences ; Cluster Analysis ; Fundamental and applied biological sciences. 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Recombination contributes to an increase in genetic variation and hinders vaccine design efforts. Several molecular epidemiology studies in South America described the circulation of subtypes B, F, and C as well as several B/F1 recombinants. This study performed by nucleotide sequencing in at least two genes of 89 samples from Uruguay has shown a complex HIV-1 epidemic characterized by the cocirculation of subtype B, and subtype C strains, together with an important group of BF1 recombinant viruses, including isolates similar to CRF12_BF. In addition we identified a new circulating recombinant form, designated CRF38_BF(1), which was dominant in the recombinant virus group.</description><subject>AIDS/HIV</subject><subject>Biological and medical sciences</subject><subject>Cluster Analysis</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetic recombination</subject><subject>Genotype</subject><subject>HIV (Viruses)</subject><subject>HIV Infections - virology</subject><subject>HIV-1 - classification</subject><subject>HIV-1 - genetics</subject><subject>HIV-1 - isolation & purification</subject><subject>Human immunodeficiency virus 1</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Identification and classification</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Miscellaneous</subject><subject>Molecular evolution</subject><subject>Molecular Sequence Data</subject><subject>Phylogeny</subject><subject>Physiological aspects</subject><subject>Recombination, Genetic</subject><subject>Retrovirus</subject><subject>Sequence Analysis, DNA</subject><subject>Sequence Homology</subject><subject>Uruguay</subject><subject>Viral diseases</subject><subject>Virology</subject><issn>0889-2229</issn><issn>1931-8405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0c9rFDEUB_Agit1Wj14lIIoeZs2vySTHunTtQkEoba8hySRLZCZZkxlk_3sz7KIIguQQSD7vkbwvAG8wWmMk5Gcd-jVBSKwRYeIZWGFJcSMYap-DFRJCNoQQeQEuS_mOEJKEtC_BRUWkQ227Ak-73sUp-GD1FFKEyUMNo_sJb3dP8OF4cBDDTch2Hup93MN7Z9NoQtRxgtuUR_hxc7-lQn3Z4k8wRPiY5_2sj6_AC6-H4l6f9yvwuL152Nw2d9--7jbXd41lWE6NM0IL4qRhRlqKddcJyqThzFsnhelaTJnxxmPJSP2ScVgI7YShnHdS9pxegQ-nvoecfsyuTGoMxbph0NGluSje1Rlw3P0XEtRSUsdW4bsT3OvBqRB9mrK2C1bXWAqGGeVLu_U_VF29G4NN0flQz_8qaE4FNqdSsvPqkMOo81FhpJYgVQ1SLUGqJcjq357fO5vR9X_0ObkK3p-BLlYPPutoQ_ntCKYd56KlvwBzTqFl</recordid><startdate>20090301</startdate><enddate>20090301</enddate><creator>RUCHANSKY, Dora</creator><creator>CASADO, Concepcion</creator><creator>RUSSI, José C</creator><creator>ARBIZA, Juan R</creator><creator>LOPEZ-GALINDEZ, Cecilio</creator><general>Liebert</general><general>Mary Ann Liebert, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20090301</creationdate><title>Identification of a new HIV Type 1 Circulating Recombinant Form (CRF38_BF1) in Uruguay</title><author>RUCHANSKY, Dora ; CASADO, Concepcion ; RUSSI, José C ; ARBIZA, Juan R ; LOPEZ-GALINDEZ, Cecilio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-eb8a82e9b4b9c31a778349b64fce98b75134bfbf1942405be188ae8b366799d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>AIDS/HIV</topic><topic>Biological and medical sciences</topic><topic>Cluster Analysis</topic><topic>Fundamental and applied biological sciences. 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| ispartof | AIDS research and human retroviruses, 2009-03, Vol.25 (3), p.351-356 |
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| language | eng |
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| source | Mary Ann Liebert Online Subscription; MEDLINE; Alma/SFX Local Collection |
| subjects | AIDS/HIV Biological and medical sciences Cluster Analysis Fundamental and applied biological sciences. Psychology Genetic recombination Genotype HIV (Viruses) HIV Infections - virology HIV-1 - classification HIV-1 - genetics HIV-1 - isolation & purification Human immunodeficiency virus 1 Human viral diseases Humans Identification and classification Infectious diseases Medical sciences Microbiology Miscellaneous Molecular evolution Molecular Sequence Data Phylogeny Physiological aspects Recombination, Genetic Retrovirus Sequence Analysis, DNA Sequence Homology Uruguay Viral diseases Virology |
| title | Identification of a new HIV Type 1 Circulating Recombinant Form (CRF38_BF1) in Uruguay |
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