Gene expression profiling of pediatric acute myelogenous leukemia

Contemporary treatment of pediatric acute myeloid leukemia (AML) requires the assignment of patients to specific risk groups. To explore whether expression profiling of leukemic blasts could accurately distinguish between the known risk groups of AML, we analyzed 130 pediatric and 20 adult AML diagn...

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Veröffentlicht in:	Blood 2004-12, Vol.104 (12), p.3679-3687
Hauptverfasser:	Ross, Mary E., Mahfouz, Rami, Onciu, Mihaela, Liu, Hsi-Che, Zhou, Xiaodong, Song, Guangchun, Shurtleff, Sheila A., Pounds, Stanley, Cheng, Cheng, Ma, Jing, Ribeiro, Raul C., Rubnitz, Jeffrey E., Girtman, Kevin, Williams, W. Kent, Raimondi, Susana C., Liang, Der-Cherng, Shih, Lee-Yung, Pui, Ching-Hon, Downing, James R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Algorithms Biological and medical sciences Blood Bone Marrow Child Cluster Analysis DNA-Binding Proteins - genetics Gene Expression Profiling Hematologic and hematopoietic diseases Histone-Lysine N-Methyltransferase Humans Leukemia, Myeloid, Acute - classification Leukemia, Myeloid, Acute - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Myeloid-Lymphoid Leukemia Protein Oncogene Proteins, Fusion - genetics Prognosis Proto-Oncogenes - genetics Risk Factors Tandem Repeat Sequences Transcription Factors - genetics
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