Identification of CCDC62‐2 as a novel cancer/testis antigen and its immunogenicity

Cancer/testis (CT) antigens are expressed in normal germ line tissues and various cancers. They are considered promising target molecules for immunotherapy for patients with various cancers. To identify CT antigens, we performed serological identification of antigens by recombinant expression clonin...

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Veröffentlicht in:	International journal of cancer 2009-05, Vol.124 (10), p.2347-2352
Hauptverfasser:	Domae, Shohei, Nakamura, Yoichi, Nakamura, Yurika, Uenaka, Akiko, Wada, Hisashi, Nakata, Masao, Oka, Mikio, Kishimoto, Koji, Tsukamoto, Goichi, Yoshihama, Yasuto, Matsuoka, Junji, Gochi, Akira, Kohno, Shigeru, Saika, Takashi, Sasaki, Akira, Nakayama, Eiichi, Ono, Toshiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - immunology Aged antibody response Antigens, Neoplasm - biosynthesis Antigens, Neoplasm - genetics Antigens, Neoplasm - immunology Base Sequence Biological and medical sciences Blotting, Western cancer/testis antigen CCDC62‐2 DNA Primers DNA, Complementary Enzyme-Linked Immunosorbent Assay Humans Male Medical sciences Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Recombinant Proteins - immunology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics SEREX Stomach Neoplasms - immunology Testis - immunology Transcription Factors - biosynthesis Transcription Factors - genetics Transcription Factors - immunology Tumors
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