Increased FcgammaRII expression and aberrant tumour necrosis factor alpha production by mature dendritic cells from patients with active rheumatoid arthritis

To investigate potential differences in phenotype and behaviour of immature (iDC) and mature dendritic cells (mDC) from patients with RA and healthy subjects. iDC and mDC were derived from blood monocytes of patients with RA and healthy controls following standardised protocols. FACS was used to ana...

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Veröffentlicht in:	Annals of the rheumatic diseases 2004-12, Vol.63 (12), p.1556-1563
Hauptverfasser:	Radstake, T R D J, Blom, A B, Slöetjes, A W, van Gorselen, E O F, Pesman, G J, Engelen, L, Torensma, R, van den Berg, W B, Figdor, C G, van Lent, P L E M, Adema, G J, Barrera, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-Antibody Complex - immunology Arthritis, Rheumatoid - immunology Cell Differentiation - immunology Cells, Cultured Dendritic Cells - immunology Gene Expression Humans Receptors, IgG - genetics Receptors, IgG - metabolism RNA, Messenger - genetics Synovial Membrane - immunology Tumor Necrosis Factor-alpha - biosynthesis Up-Regulation - immunology
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