Predictors of Loss of Virologic Response in Subjects Who Simplified to Lopinavir/Ritonavir Monotherapy from Lopinavir/Ritonavir Plus Zidovudine/Lamivudine

Previous studies have demonstrated that lopinavir/ritonavir monotherapy maintained plasma HIV-1 RNA suppression in a large proportion of antiretroviral naive subjects. However, more subjects receiving lopinavir/ritonavir monotherapy experienced confirmed virologic rebound >50 copies/ml compared t...

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Veröffentlicht in:	AIDS research and human retroviruses 2009-03, Vol.25 (3), p.269-275
Hauptverfasser:	CAMPO, Rafael E, DA SILVA, Barbara A, COTTE, Laurent, GATHE, Joseph C, GAZZARD, Brian, HICKS, Charles B, KLEIN, Cheri E, CHIU, Yi-Lin, KING, Martin S, BERNSTEIN, Barry M
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Anti-HIV agents Anti-HIV Agents - therapeutic use Antiretroviral Therapy, Highly Active - methods Antiviral agents Biological and medical sciences CD4 Lymphocyte Count Complications and side effects Dosage and administration Drug therapy Drug therapy, Combination Fundamental and applied biological sciences. Psychology Health aspects HIV infection HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 - drug effects Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Lamivudine - therapeutic use Lopinavir Medical sciences Medication Adherence - statistics & numerical data Microbiology Miscellaneous Plasma - chemistry Pyrimidinones - blood Pyrimidinones - therapeutic use Retrovirus Ritonavir - therapeutic use Time Factors Treatment Outcome Viral diseases Viral Load Virology Zidovudine - therapeutic use
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