Increased incidence of monoclonal B-cell infiltrate in chronic myeloproliferative disorders

A total of 106 trephine biopsy specimens with clinical, laboratory and pathology findings corresponding to chronic myeloproliferative disorders (CMPD) were analyzed to reveal the nature of the lymphoid infiltrate in the bone marrow. Histological investigation in 31 chronic myeloid leukemia (CML), 29...

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Veröffentlicht in:	Modern pathology 2004-12, Vol.17 (12), p.1521-1530
Hauptverfasser:	Pajor, László, Lacza, Ágnes, Kereskai, László, Jáksó, Pál, Egyed, Miklós, Iványi, János L, Radványi, Gáspár, Dombi, Péter, Pál, Katalin, Losonczy, Hajna
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - immunology B-Lymphocytes - pathology CD3 Complex - analysis CD5 Antigens - analysis Chronic Disease DNA - analysis DNA - genetics DNA - isolation & purification Flow Cytometry Fusion Proteins, bcr-abl - genetics Gene Expression Gene Rearrangement, B-Lymphocyte, Heavy Chain - genetics Humans immunoglobulin gene Immunoglobulin kappa-Chains - analysis Immunoglobulin lambda-Chains - analysis In Situ Hybridization, Fluorescence Laboratory Medicine Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - immunology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology lymphoma Medicine Medicine & Public Health myeloproliferation Myeloproliferative Disorders - genetics Myeloproliferative Disorders - immunology Myeloproliferative Disorders - pathology Neprilysin - analysis original-article Pathology Polycythemia Vera - genetics Polycythemia Vera - immunology Polycythemia Vera - pathology Polymerase Chain Reaction Receptors, IgE - analysis Thrombocytosis - genetics Thrombocytosis - immunology Thrombocytosis - pathology
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