Sequence alterations in the YBX2 gene are associated with male factor infertility

Objective To investigate YBX2 gene alterations in men with severe defects in spermatogenesis, including azoospermia or severe oligozoospermia, and protamine deregulation. MSY2 has been identified as a central component in the regulation of spermatogenesis in mice, but the potential role of its human...

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Veröffentlicht in:	Fertility and sterility 2009-04, Vol.91 (4), p.1090-1095
Hauptverfasser:	Hammoud, Sue, B.S, Emery, Benjamin R., B.S, Dunn, Diane, M.S, Weiss, Robert B., Ph.D, Carrell, Douglas T., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - genetics Biological and medical sciences Birth control Case-Control Studies Cohort Studies Contrin DNA Mutational Analysis Gene Frequency Genetic Linkage Genotype Gynecology. Andrology. Obstetrics Humans Infertility, Male - genetics Infertility, Male - metabolism Internal Medicine Male Medical sciences Obstetrics and Gynecology Polymorphism, Single Nucleotide - physiology protamine Protamines - genetics Protamines - metabolism RNA-Binding Proteins - genetics SNPs spermatogenesis Spermatogenesis - genetics Sterility. Assisted procreation transcription factor translation regulation YBX2
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