Highly Ordered Supra-Molecular Organization of the Mycobacterial Lipoarabinomannans in Solution. Evidence of a Relationship Between Supra-Molecular Organization and Biological Activity

The complex mycobacterial mannosylated lipoarabinomannans (ManLAMs) are currently considered to be the major virulence factors of the pathogenic Mycobacterium tuberculosis. The recognition and the interaction of ManLAMs with immune system receptors have been shown to promote M. tuberculosis phagocyt...

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