Liver biopsies from human females contain male hepatocytes in the absence of transplantation

Fetal cells derived from pregnancy can persist in a woman's blood and tissues for decades and have been implicated in the pathogenesis of autoimmune disease. Transplantation studies based on donor sex mismatch suggest that circulating stem cells can lead to liver regeneration with donor-derived...

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Veröffentlicht in:	Laboratory investigation 2004-12, Vol.84 (12), p.1603-1609
Hauptverfasser:	Stevens, Anne M, Michael McDonnell, W, Mullarkey, Meghan E, Pang, Jennifer M, Leisenring, Wendy, Lee Nelson, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult autoimmunity Biological and medical sciences Biotechnology Female fetal Fundamental and applied biological sciences. Psychology Hepatocytes - cytology Humans Investigative techniques, diagnostic techniques (general aspects) liver Liver - physiology Male Medical sciences microchimerism Middle Aged Mosaicism Phenotype Pregnancy transplantation
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