Collagen antibody-induced arthritis in mice: Development of a new arthritogenic 5-clone cocktail of monoclonal anti-type II collagen antibodies

A cocktail of 4 monoclonal anti-type II collagen antibodies recognizing conserved epitopes located within the CB11 fragment (CII 124-402) of type II collagen is currently used as an arthritogenic antibody preparation for inducing collagen antibody induced arthritis (CAIA). In order to increase the a...

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Veröffentlicht in:	Journal of immunological methods 2009-03, Vol.343 (1), p.49-55
Hauptverfasser:	Hutamekalin, Pilaiwanwadee, Saito, Takayuki, Yamaki, Kouya, Mizutani, Nobuaki, Brand, David D., Waritani, Takaki, Terato, Kuniaki, Yoshino, Shin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic - immunology Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - immunology Arthritis, Experimental - immunology Arthritogenic epitope Arthritogenicity Biological and medical sciences CAIA Cattle CIA Collagen Type II - immunology Disease Models, Animal Epitopes - analysis Epitopes - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Hybridomas - immunology Male Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred DBA Molecular immunology Monoclonal antibody Rheumatoid arthritis Species Specificity Techniques
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