Assessment of iron distribution between liver, spleen, pancreas, bone marrow, and myocardium by means of R2 relaxometry with MRI in patients with β-thalassemia major

Purpose To investigate the correlation between the degree of hepatic, splenic, pancreatic, vertebral bone marrow (VBM), and myocardial siderosis, as expressed by relaxation rate (R2 = 1/T2) values, in patients with thalassemia. Materials and Methods R2 relaxation rate values of liver, spleen, VBM, p...

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Veröffentlicht in:	Journal of magnetic resonance imaging 2009-04, Vol.29 (4), p.853-859
Hauptverfasser:	Papakonstantinou, Olympia, Alexopoulou, Efthymia, Economopoulos, Nikos, Benekos, Odysseas, Kattamis, Antonis, Kostaridou, Stavroula, Ladis, Vasilis, Efstathopoulos, Efstathios, Gouliamos, Athanassios, Kelekis, Nikolaos L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult beta-Thalassemia - complications Bone Marrow - metabolism Child Female Humans Image Processing, Computer-Assisted Iron - metabolism iron overload Iron Overload - diagnosis Iron Overload - etiology Liver - metabolism Magnetic Resonance Imaging - methods Male MRI Myocardium - metabolism Pancreas - metabolism R2 relaxometry Spleen - metabolism thalassemia
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