Antituberculosis drug resistance and associated risk factors in the European section of Turkey

We carried out this study in order to establish the prevalence of antituberculosis drug resistance in Mycobacterium tuberculosis strains and to determine risk factors for the development of resistance in Trakya region of Turkey. Pattern of drug resistance in 214 M. tuberculosis isolates from patient...

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Veröffentlicht in:Indian journal of chest diseases & allied sciences 2004-07, Vol.46 (3), p.171-177
Hauptverfasser: Karabay, Oguz, Otkun, Metin, Akata, Filiz, Karlikaya, Celal, Tuğrul, Murat, Dündar, Volkan
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Sprache:eng
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Zusammenfassung:We carried out this study in order to establish the prevalence of antituberculosis drug resistance in Mycobacterium tuberculosis strains and to determine risk factors for the development of resistance in Trakya region of Turkey. Pattern of drug resistance in 214 M. tuberculosis isolates from patients with tuberculosis treated at the regional tuberculosis dispensaries were included in the study. Isolates of 105 (49.1%) were resistant to only one drug, and 62 (29.0%) were resistant to more than one drug. The total resistance rates to streptomycin, isoniazid, rifampicin, ethambutol and isoniazid + rifampicin were 29.0%, 27.1%, 21.5%, 10.3% and 11.6%, respectively. The secondary resistance rates in all drugs and combinations were higher than primary resistance rates (p
ISSN:0377-9343