Antinociceptive Properties of the Hydroalcoholic Extract and the Flavonoid Rutin Obtained from Polygala paniculata L. in Mice

: The present study examined the antinociceptive effects of a hydroalcoholic extract of Polygala paniculata in chemical and thermal behavioural models of pain in mice. The antinociceptive effects of hydroalcoholic extract was evaluated in chemical (acetic‐acid, formalin, capsaicin, cinnamaldehyde...

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Veröffentlicht in:	Basic & clinical pharmacology & toxicology 2009-04, Vol.104 (4), p.306-315
Hauptverfasser:	Lapa, Fernanda da R., Gadotti, Vinicius M., Missau, Fabiana C., Pizzolatti, Moacir G., Marques, Maria Consuelo A., Dafré, Alcir L., Farina, Marcelo, Rodrigues, Ana Lúcia S., Santos, Adair R. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Analgesics - administration & dosage Analgesics - isolation & purification Analgesics - pharmacology Animals Behavior, Animal - drug effects Biological and medical sciences Disease Models, Animal Dose-Response Relationship, Drug Injections, Intraperitoneal Male Medical sciences Mice Pain - drug therapy Pain Measurement Pharmacology. Drug treatments Plant Extracts - administration & dosage Plant Extracts - pharmacology Polygala - chemistry Polygala paniculata Receptors, Glutamate - drug effects Receptors, Glutamate - metabolism Rutin - administration & dosage Rutin - isolation & purification Rutin - pharmacology
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