Heterochromatin Regulates Cell Type-Specific Long-Range Chromatin Interactions Essential for Directed Recombination

Mating-type switching in Schizosaccharomyces pombe involves replacing genetic information at the expressed mat1 locus with sequences copied from one of two silent donor loci, mat2-P or mat3-M, located within a 20-kb heterochromatic domain. Donor selection is dictated by cell type: mat2 is the prefer...

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Veröffentlicht in:	Cell 2004-11, Vol.119 (4), p.469-480
Hauptverfasser:	Jia, Songtao, Yamada, Takatomi, Grewal, Shiv I.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Communication Chromatin - physiology Chromosomal Proteins, Non-Histone - metabolism Chromosome Mapping DNA-Binding Proteins - metabolism DNA-Binding Proteins - physiology Gene Expression Regulation, Fungal Genes, Fungal Genes, Mating Type, Fungal Genes, Regulator Genes, Switch Heterochromatin - physiology Models, Genetic Recombination, Genetic Schizosaccharomyces - cytology Schizosaccharomyces - genetics Schizosaccharomyces pombe Schizosaccharomyces pombe Proteins - metabolism Transcription Factors - metabolism Transcription Factors - physiology
Online-Zugang:	Volltext
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