The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast

A genetically defined pathway orchestrates the removal of 131 of the 1090 somatic cells generated during the development of the hermaphrodite nematode Caenorhabditis elegans . Regulation of apoptosis is highly evolutionarily conserved and the nematode cell death pathway is a valuable model for study...

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Veröffentlicht in:	Cell death and differentiation 2004-12, Vol.11 (12), p.1309-1316
Hauptverfasser:	Jabbour, A M, Ho, P-k, Puryer, M A, Ashley, D M, Ekert, P G, Hawkins, C J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - physiology Apoptosis Regulatory Proteins Biochemistry Biomedical and Life Sciences Caenorhabditis elegans Caenorhabditis elegans Proteins - chemistry Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Caspases - chemistry Caspases - genetics Caspases - metabolism Cell Biology Cell Cycle Analysis Enzyme Activation - physiology Feedback, Physiological - physiology Gene Expression Regulation, Fungal - physiology In Vitro Techniques Life Sciences original-paper Proto-Oncogene Proteins - chemistry Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-bcl-2 Saccharomyces cerevisiae - metabolism Signal Transduction - physiology Stem Cells
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