Intrapleural Injection of Transforming Growth Factor-β Antibody Inhibits Pleural Fibrosis in Empyema

Transforming growth factor (TGF)-β is a cytokine that has been demonstrated to be an important modulator of inflammation and angiogenesis, as well as a potent stimulator of pleural fluid production and fibrosis. We previously demonstrated that rising levels of pleural fluid TGF-β1 correlate with ple...

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Veröffentlicht in:	Chest 2004-11, Vol.126 (5), p.1636-1644
Hauptverfasser:	Kunz, Craig R., Jadus, Martin R., Kukes, Gary D., Kramer, Françoise, Nguyen, Vu N., Sasse, Scott A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cardiology. Vascular system cytokines empyema Empyema, Pleural - complications Fibrosis Injections, Intralesional Male Medical sciences Pleura - pathology pleural Pleural Diseases - etiology Pleural Diseases - pathology Pleural Diseases - prevention & control Pneumology Prospective Studies Rabbits Random Allocation Respiratory system : syndromes and miscellaneous diseases Transforming Growth Factor beta - administration & dosage
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