A modified gonadotropin-releasing hormone (GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol
The purpose of this prospective randomized study was to compare stimulation characteristics and IVF outcomes of the standard long GnRH agonist protocol for ovarian stimulation with a modified GnRH antagonist protocol. Starting GnRH antagonist in a flexible protocol according to the size of the leadi...
Gespeichert in:
| Veröffentlicht in: | Fertility and sterility 2004-11, Vol.82 (5), p.1446-1448 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1448 |
|---|---|
| container_issue | 5 |
| container_start_page | 1446 |
| container_title | Fertility and sterility |
| container_volume | 82 |
| creator | Loutradis, Dimitris Stefanidis, Konstantinos Drakakis, Peter Milingos, Spyridon Antsaklis, Aris Michalas, Stylianos |
| description | The purpose of this prospective randomized study was to compare stimulation characteristics and IVF outcomes of the standard long GnRH agonist protocol for ovarian stimulation with a modified GnRH antagonist protocol. Starting GnRH antagonist in a flexible protocol according to the size of the leading follicle, with simultaneous augmentation of 75 IU recombinant FSH, failed to increase clinical pregnancy rates. |
| doi_str_mv | 10.1016/j.fertnstert.2004.04.051 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67060695</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0015028204022551</els_id><sourcerecordid>67060695</sourcerecordid><originalsourceid>FETCH-LOGICAL-c420t-8533c86a5d36ac65e4015ea4531c4deb3b4868bda952366f6aff912092be7aea3</originalsourceid><addsrcrecordid>eNqFkVFrFDEUhYModlv9C5In0YdZk8kkM_tYi22FgiD6HO4kd3azZJI1yVb6V_y1ZtjFPgqX5OU753A4hFDO1pxx9Wm_njCVkEt91y1j3Xo5yV-QFZdSNVJJ8ZKsGOOyYe3QXpDLnPeMMcX79jW5qJAQou9X5M81naN1k0NLtzGAjSXFgwtNQo-QXdjSXUxzDEg_3IXv9x8phAKVdLnQQ4olmujpBM5XgxKpCyZVHVLjXXAGfIVwGyCYJ5qgYK4ENXE-QHI5BvrblR0tO6Q-1qgl4Z_rG_JqAp_x7fm_Ij9vv_y4uW8evt19vbl-aEzXstIMtYoZFEgrFBglsautETopuOksjmLsBjWMFjayFUpNCqZpw1u2aUfsAUFckfcn3xr864i56Nllg95DwHjMWvVMMbWRFRxOoEkx54STPiQ3Q3rSnOllF73Xz7voZRe9nORV-u6ccRxntM_C8xAV-HwCsDZ9dJh0Ng6DQesSmqJtdP9P-QsOLagI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67060695</pqid></control><display><type>article</type><title>A modified gonadotropin-releasing hormone (GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Loutradis, Dimitris ; Stefanidis, Konstantinos ; Drakakis, Peter ; Milingos, Spyridon ; Antsaklis, Aris ; Michalas, Stylianos</creator><creatorcontrib>Loutradis, Dimitris ; Stefanidis, Konstantinos ; Drakakis, Peter ; Milingos, Spyridon ; Antsaklis, Aris ; Michalas, Stylianos</creatorcontrib><description>The purpose of this prospective randomized study was to compare stimulation characteristics and IVF outcomes of the standard long GnRH agonist protocol for ovarian stimulation with a modified GnRH antagonist protocol. Starting GnRH antagonist in a flexible protocol according to the size of the leading follicle, with simultaneous augmentation of 75 IU recombinant FSH, failed to increase clinical pregnancy rates.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2004.04.051</identifier><identifier>PMID: 15533377</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Clinical Protocols ; Female ; Gonadotropin-Releasing Hormone - agonists ; Gonadotropin-Releasing Hormone - analogs & derivatives ; Gonadotropin-Releasing Hormone - antagonists & inhibitors ; Gonadotropin-Releasing Hormone - therapeutic use ; Hormone Antagonists - therapeutic use ; Humans ; Pregnancy ; Pregnancy Rate ; Time Factors ; Triptorelin Pamoate - therapeutic use</subject><ispartof>Fertility and sterility, 2004-11, Vol.82 (5), p.1446-1448</ispartof><rights>2004 American Society for Reproductive Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-8533c86a5d36ac65e4015ea4531c4deb3b4868bda952366f6aff912092be7aea3</citedby><cites>FETCH-LOGICAL-c420t-8533c86a5d36ac65e4015ea4531c4deb3b4868bda952366f6aff912092be7aea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fertnstert.2004.04.051$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27907,27908,45978</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15533377$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Loutradis, Dimitris</creatorcontrib><creatorcontrib>Stefanidis, Konstantinos</creatorcontrib><creatorcontrib>Drakakis, Peter</creatorcontrib><creatorcontrib>Milingos, Spyridon</creatorcontrib><creatorcontrib>Antsaklis, Aris</creatorcontrib><creatorcontrib>Michalas, Stylianos</creatorcontrib><title>A modified gonadotropin-releasing hormone (GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>The purpose of this prospective randomized study was to compare stimulation characteristics and IVF outcomes of the standard long GnRH agonist protocol for ovarian stimulation with a modified GnRH antagonist protocol. Starting GnRH antagonist in a flexible protocol according to the size of the leading follicle, with simultaneous augmentation of 75 IU recombinant FSH, failed to increase clinical pregnancy rates.</description><subject>Adult</subject><subject>Clinical Protocols</subject><subject>Female</subject><subject>Gonadotropin-Releasing Hormone - agonists</subject><subject>Gonadotropin-Releasing Hormone - analogs & derivatives</subject><subject>Gonadotropin-Releasing Hormone - antagonists & inhibitors</subject><subject>Gonadotropin-Releasing Hormone - therapeutic use</subject><subject>Hormone Antagonists - therapeutic use</subject><subject>Humans</subject><subject>Pregnancy</subject><subject>Pregnancy Rate</subject><subject>Time Factors</subject><subject>Triptorelin Pamoate - therapeutic use</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkVFrFDEUhYModlv9C5In0YdZk8kkM_tYi22FgiD6HO4kd3azZJI1yVb6V_y1ZtjFPgqX5OU753A4hFDO1pxx9Wm_njCVkEt91y1j3Xo5yV-QFZdSNVJJ8ZKsGOOyYe3QXpDLnPeMMcX79jW5qJAQou9X5M81naN1k0NLtzGAjSXFgwtNQo-QXdjSXUxzDEg_3IXv9x8phAKVdLnQQ4olmujpBM5XgxKpCyZVHVLjXXAGfIVwGyCYJ5qgYK4ENXE-QHI5BvrblR0tO6Q-1qgl4Z_rG_JqAp_x7fm_Ij9vv_y4uW8evt19vbl-aEzXstIMtYoZFEgrFBglsautETopuOksjmLsBjWMFjayFUpNCqZpw1u2aUfsAUFckfcn3xr864i56Nllg95DwHjMWvVMMbWRFRxOoEkx54STPiQ3Q3rSnOllF73Xz7voZRe9nORV-u6ccRxntM_C8xAV-HwCsDZ9dJh0Ng6DQesSmqJtdP9P-QsOLagI</recordid><startdate>20041101</startdate><enddate>20041101</enddate><creator>Loutradis, Dimitris</creator><creator>Stefanidis, Konstantinos</creator><creator>Drakakis, Peter</creator><creator>Milingos, Spyridon</creator><creator>Antsaklis, Aris</creator><creator>Michalas, Stylianos</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20041101</creationdate><title>A modified gonadotropin-releasing hormone (GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol</title><author>Loutradis, Dimitris ; Stefanidis, Konstantinos ; Drakakis, Peter ; Milingos, Spyridon ; Antsaklis, Aris ; Michalas, Stylianos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-8533c86a5d36ac65e4015ea4531c4deb3b4868bda952366f6aff912092be7aea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Clinical Protocols</topic><topic>Female</topic><topic>Gonadotropin-Releasing Hormone - agonists</topic><topic>Gonadotropin-Releasing Hormone - analogs & derivatives</topic><topic>Gonadotropin-Releasing Hormone - antagonists & inhibitors</topic><topic>Gonadotropin-Releasing Hormone - therapeutic use</topic><topic>Hormone Antagonists - therapeutic use</topic><topic>Humans</topic><topic>Pregnancy</topic><topic>Pregnancy Rate</topic><topic>Time Factors</topic><topic>Triptorelin Pamoate - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Loutradis, Dimitris</creatorcontrib><creatorcontrib>Stefanidis, Konstantinos</creatorcontrib><creatorcontrib>Drakakis, Peter</creatorcontrib><creatorcontrib>Milingos, Spyridon</creatorcontrib><creatorcontrib>Antsaklis, Aris</creatorcontrib><creatorcontrib>Michalas, Stylianos</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Loutradis, Dimitris</au><au>Stefanidis, Konstantinos</au><au>Drakakis, Peter</au><au>Milingos, Spyridon</au><au>Antsaklis, Aris</au><au>Michalas, Stylianos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A modified gonadotropin-releasing hormone (GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2004-11-01</date><risdate>2004</risdate><volume>82</volume><issue>5</issue><spage>1446</spage><epage>1448</epage><pages>1446-1448</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><abstract>The purpose of this prospective randomized study was to compare stimulation characteristics and IVF outcomes of the standard long GnRH agonist protocol for ovarian stimulation with a modified GnRH antagonist protocol. Starting GnRH antagonist in a flexible protocol according to the size of the leading follicle, with simultaneous augmentation of 75 IU recombinant FSH, failed to increase clinical pregnancy rates.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>15533377</pmid><doi>10.1016/j.fertnstert.2004.04.051</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0015-0282 |
| ispartof | Fertility and sterility, 2004-11, Vol.82 (5), p.1446-1448 |
| issn | 0015-0282 1556-5653 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67060695 |
| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Clinical Protocols Female Gonadotropin-Releasing Hormone - agonists Gonadotropin-Releasing Hormone - analogs & derivatives Gonadotropin-Releasing Hormone - antagonists & inhibitors Gonadotropin-Releasing Hormone - therapeutic use Hormone Antagonists - therapeutic use Humans Pregnancy Pregnancy Rate Time Factors Triptorelin Pamoate - therapeutic use |
| title | A modified gonadotropin-releasing hormone (GnRH) antagonist protocol failed to increase clinical pregnancy rates in comparison with the long GnRH protocol |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T07%3A44%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20modified%20gonadotropin-releasing%20hormone%20(GnRH)%20antagonist%20protocol%20failed%20to%20increase%20clinical%20pregnancy%20rates%20in%20comparison%20with%20the%20long%20GnRH%20protocol&rft.jtitle=Fertility%20and%20sterility&rft.au=Loutradis,%20Dimitris&rft.date=2004-11-01&rft.volume=82&rft.issue=5&rft.spage=1446&rft.epage=1448&rft.pages=1446-1448&rft.issn=0015-0282&rft.eissn=1556-5653&rft_id=info:doi/10.1016/j.fertnstert.2004.04.051&rft_dat=%3Cproquest_cross%3E67060695%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67060695&rft_id=info:pmid/15533377&rft_els_id=S0015028204022551&rfr_iscdi=true |