Development of endotoxin tolerance in humans in vivo

OBJECTIVE:Endotoxin (lipopolysaccharide [LPS]) tolerance is characterized by a reduced responsiveness to a subsequent LPS challenge. In animal and human in vitro experiments, LPS tolerance is associated with an attenuated response of proinflammatory cytokines and an enhanced production of anti-infla...

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Veröffentlicht in:	Critical care medicine 2009-04, Vol.37 (4), p.1261-1267
Hauptverfasser:	Draisma, Annelies, Pickkers, Peter, Bouw, Martijn P.W.J.M, van der Hoeven, Johannes G
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood coagulation. Blood cells Cytokines - biosynthesis Escherichia coli Fundamental and applied biological sciences. Psychology Humans Immune Tolerance Intensive care medicine Lipopolysaccharides - immunology Lipopolysaccharides - pharmacology Male Medical sciences Molecular and cellular biology Platelet Young Adult
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