Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia

Background. Vascular calcification has been widely recognized as a significant contributor to cardiovascular risk in patients with chronic kidney disease. Recent evidence suggests that BMP-7 decreases the vascular calcification observed in uraemic rats, while BMP-2 could also be participating in thi...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2009-04, Vol.24 (4), p.1121-1129
Hauptverfasser:	Jara, Aquiles, Chacón, Cecilia, Burgos, María Eugenia, Droguett, Alejandra, Valdivieso, Andrés, Ortiz, Mireya, Troncoso, Pablo, Mezzano, Sergio
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Aortic Diseases - pathology Aortic Diseases - physiopathology Biological and medical sciences BMP-2 BMP-7 antagonist Bone Morphogenetic Proteins - antagonists & inhibitors Calcinosis - physiopathology CKD Disease Models, Animal Emergency and intensive care: renal failure. Dialysis management gremlin Intensive care medicine Intercellular Signaling Peptides and Proteins - biosynthesis Kidney Transplantation Male Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Rats Rats, Sprague-Dawley Renal failure Uremia - complications Uremia - surgery vascular calcification
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