Sandwich ELISA system for cartilage oligomeric matrix protein in equine synovial fluid and serum

Summary Reasons for performing study: Measurement of cartilage oligomeric matrix protein (COMP) in serum has potential for diagnosis of equine osteoarthritis (OA), but clinical use is currently limited by the lack of specificity of an inhibition ELISA as well as by baseline increases due to exercise...

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Bibliographische Detailangaben
Veröffentlicht in:	Equine veterinary journal 2009, Vol.41 (1), p.41-46
Hauptverfasser:	Yamanokuchi, K, Tagami, M, Nishimatsu, E, Shimizu, Y, Hirose, Y, Komatsu, K, Misumi, K
Format:	Artikel
Sprache:	eng
Schlagworte:	animal proteins Animals Antibodies, Monoclonal - immunology antibody biomarkers Biomarkers - analysis blood proteins blood serum cartilage cartilage oligomeric matrix protein Case-Control Studies COMP disease diagnosis ELISA enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - veterinary Epitope Mapping - veterinary epitopes Extracellular Matrix Proteins - analysis Extracellular Matrix Proteins - blood Extracellular Matrix Proteins - immunology Female Glycoproteins - analysis Glycoproteins - blood Glycoproteins - immunology horse horse diseases Horse Diseases - blood Horse Diseases - diagnosis Horses Matrilin Proteins Mice Mice, Inbred BALB C monoclonal antibodies osteoarthritis Osteoarthritis - blood Osteoarthritis - diagnosis Osteoarthritis - veterinary sandwich enzyme-linked immunosorbent assay Sensitivity and Specificity synovial fluid Synovial Fluid - chemistry Synovial Fluid - metabolism
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