Cutting Edge: Acute Lung Allograft Rejection Is Independent of Secondary Lymphoid Organs

It is the prevailing view that adaptive immune responses are initiated in secondary lymphoid organs. Studies using alymphoplastic mice have shown that secondary lymphoid organs are essential to initiate allograft rejection of skin, heart, and small bowel. The high immunogenicity of lungs is well rec...

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Veröffentlicht in:	The Journal of immunology (1950) 2009-04, Vol.182 (7), p.3969-3973
Hauptverfasser:	Gelman, Andrew E, Li, Wenjun, Richardson, Steven B, Zinselmeyer, Bernd H, Lai, Jiaming, Okazaki, Mikio, Kornfeld, Christopher G, Kreisel, Friederike H, Sugimoto, Seiichiro, Tietjens, Jeremy R, Dempster, John, Patterson, G. Alexander, Krupnick, Alexander S, Miller, Mark J, Kreisel, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Graft Rejection - immunology Immunohistochemistry Lung Transplantation - immunology Lymphocyte Activation - immunology Lymphoid Tissue - immunology Mice Microscopy, Fluorescence T-Lymphocytes - immunology Transplantation, Homologous
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