A Reevaluation of the Role of IgM Non-HLA Antibodies in Cardiac Transplantation

Preexisting IgG antibodies to donor human leukocyte antigens (HLA) are a risk factor for rapid allograft rejection. However, non-HLA antibodies, of the IgM class, also called autoreactive antibodies, are not believed to affect graft survival. The aim of this study was to determine the incidence and...

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Veröffentlicht in:	Transplantation 2009-03, Vol.87 (6), p.864-871
Hauptverfasser:	SMITH, John D, HAMOUR, Iman M, ROSE, Marlene L, BURKE, Margaret M, MAHESH, Balikrishnan, STANFORD, Rachel E, HAJ-YAHIA, Saleem, ROBINSON, Derek R, KAUL, Pradeep, YACOUB, Magdi H, BANNER, Nicholas R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Heart Diseases - classification Heart Diseases - surgery Heart Transplantation - immunology Heart Transplantation - mortality Histocompatibility Testing HLA Antigens - immunology HLA-A Antigens - immunology HLA-B Antigens - immunology HLA-DR Antigens - immunology Humans Immunoglobulin G - blood Immunoglobulin M - blood Immunoglobulin M - immunology Isoantibodies - blood Medical sciences Middle Aged Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Survival Analysis Survivors Tissue, organ and graft immunology Transplantation, Homologous - immunology Young Adult
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