scavenger receptor MARCO is involved in Leishmania major infection by CBA/J macrophages

CBA/J mice are resistant to Leishmania major infection but are permissive to L. amazonensis infection. In addition, CBA/J macrophages control L. major but not L. amazonensis infection in vitro. Phagocytosis by macrophages is known to determine the outcome of Leishmania infection. Pattern recognition...

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Veröffentlicht in:	Parasite immunology 2009-04, Vol.31 (4), p.188-198
Hauptverfasser:	GOMES, I.N, PALMA, L.C, CAMPOS, G.O, LIMA, J.G.B, DE ALMEIDA, T.F, DE MENEZES, J.P.B, FERREIRA, C.A.G, SANTOS, R.R. DOS, BUCK, G.A, MANQUE, P.A.M, OZAKI, L.S, PROBST, C.M, DE FREITAS, L.A.R, KRIEGER, M.A, VERAS, P.S.T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - immunology Antibodies, Protozoan - metabolism Immunity, Innate Leishmania major Leishmania major - immunology Leishmania major - metabolism Leishmania mexicana - immunology Leishmania mexicana - metabolism Leishmaniasis - immunology Leishmaniasis - metabolism Leishmaniasis - parasitology Leishmaniasis - pathology Lymph Nodes - immunology Lymph Nodes - pathology macrophage Macrophages, Peritoneal - immunology Macrophages, Peritoneal - metabolism MARCO Mice Mice, Inbred CBA Receptors, Immunologic - biosynthesis Receptors, Immunologic - genetics Receptors, Immunologic - immunology Receptors, Scavenger - biosynthesis Receptors, Scavenger - genetics Receptors, Scavenger - immunology Transcriptional Activation Up-Regulation
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