Enhancement of bioactivity of Saccharomyces cerevisiae α-mating factor by attachment of sugar moiety to glutamine residue

We prepared yeast Saccharomyces cerevisiae α-mating factor, a 13-amino acid pheromone produced by haploid α-cells, bound with glucose or N-acetylglucosamine at the fifth glutamine residue from the N-terminal by the chemical method of peptide synthesis. It was found that the bioactivity of glucosyl α...

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