PIL5, a phytochrome-interacting basic helix-loop-helix protein, is a key negative regulator of seed germination in Arabidopsis thaliana
The first decision made by an angiosperm seed, whether to germinate or not, is based on integration of various environmental signals such as water and light. The phytochromes (Phys) act as red and far-red light (Pfr) photoreceptors to mediate light signaling through yet uncharacterized pathways. We...
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| Veröffentlicht in: | The Plant cell 2004-11, Vol.16 (11), p.3045-3058 |
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| creator | Oh, E Kim, J Park, E Kim, J.I Kang, C Choi, G |
| description | The first decision made by an angiosperm seed, whether to germinate or not, is based on integration of various environmental signals such as water and light. The phytochromes (Phys) act as red and far-red light (Pfr) photoreceptors to mediate light signaling through yet uncharacterized pathways. We report here that the PIF3-like 5 (PIL5) protein, a basic helix-loop-helix transcription factor, is a key negative regulator of phytochrome-mediated seed germination. PIL5 preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB). Analyses of a pil5 mutant in conjunction with phyA and phyB mutants, a pif3 pil5 double mutant, and PIL5 overexpression lines indicate that PIL5 is a negative factor in Phy-mediated promotion of seed germination, inhibition of hypocotyl negative gravitropism, and inhibition of hypocotyl elongation. Our data identify PIL5 as the first Phy-interacting protein that regulates seed germination. |
| doi_str_mv | 10.1105/tpc.104.025163 |
| format | Article |
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The phytochromes (Phys) act as red and far-red light (Pfr) photoreceptors to mediate light signaling through yet uncharacterized pathways. We report here that the PIF3-like 5 (PIL5) protein, a basic helix-loop-helix transcription factor, is a key negative regulator of phytochrome-mediated seed germination. PIL5 preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB). Analyses of a pil5 mutant in conjunction with phyA and phyB mutants, a pif3 pil5 double mutant, and PIL5 overexpression lines indicate that PIL5 is a negative factor in Phy-mediated promotion of seed germination, inhibition of hypocotyl negative gravitropism, and inhibition of hypocotyl elongation. Our data identify PIL5 as the first Phy-interacting protein that regulates seed germination.</description><identifier>ISSN: 1040-4651</identifier><identifier>ISSN: 1532-298X</identifier><identifier>EISSN: 1532-298X</identifier><identifier>DOI: 10.1105/tpc.104.025163</identifier><identifier>PMID: 15486102</identifier><language>eng</language><publisher>United States: American Society of Plant Biologists</publisher><subject>Arabidopsis - genetics ; Arabidopsis - metabolism ; Arabidopsis Proteins - genetics ; Arabidopsis Proteins - metabolism ; Arabidopsis thaliana ; Basic Helix-Loop-Helix Transcription Factors ; DNA-Binding Proteins - genetics ; DNA-Binding Proteins - metabolism ; Gene expression regulation ; Germination ; Germination - genetics ; Gravitropism ; Gravitropism - physiology ; Helix-Loop-Helix Motifs - physiology ; Hypocotyl - genetics ; Hypocotyl - growth & development ; Hypocotyl - metabolism ; Hypocotyls ; light ; Mutation - physiology ; Photoreceptor Cells - metabolism ; photoreceptors ; Physiological regulation ; phytochrome ; Phytochrome - metabolism ; Phytochrome A ; Phytochrome B ; Plant cells ; Plants ; protein-protein interactions ; Seed germination ; seedling growth ; Seedlings ; Seeds - genetics ; Seeds - metabolism ; signal transduction ; transcription factors ; Transcription Factors - genetics ; Transcription Factors - isolation & purification ; Transcription Factors - metabolism</subject><ispartof>The Plant cell, 2004-11, Vol.16 (11), p.3045-3058</ispartof><rights>Copyright 2004 American Society of Plant Biologists</rights><rights>Copyright American Society of Plant Physiologists Nov 2004</rights><rights>Copyright © 2004, American Society of Plant Biologists 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-15d0f78ac9d5a2aba0946bf74ec28b5614800fdb6f4390b5d384b2881dc0c2cb3</citedby><cites>FETCH-LOGICAL-c484t-15d0f78ac9d5a2aba0946bf74ec28b5614800fdb6f4390b5d384b2881dc0c2cb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3872284$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3872284$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,777,781,800,882,27905,27906,57998,58231</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15486102$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oh, E</creatorcontrib><creatorcontrib>Kim, J</creatorcontrib><creatorcontrib>Park, E</creatorcontrib><creatorcontrib>Kim, J.I</creatorcontrib><creatorcontrib>Kang, C</creatorcontrib><creatorcontrib>Choi, G</creatorcontrib><title>PIL5, a phytochrome-interacting basic helix-loop-helix protein, is a key negative regulator of seed germination in Arabidopsis thaliana</title><title>The Plant cell</title><addtitle>Plant Cell</addtitle><description>The first decision made by an angiosperm seed, whether to germinate or not, is based on integration of various environmental signals such as water and light. The phytochromes (Phys) act as red and far-red light (Pfr) photoreceptors to mediate light signaling through yet uncharacterized pathways. We report here that the PIF3-like 5 (PIL5) protein, a basic helix-loop-helix transcription factor, is a key negative regulator of phytochrome-mediated seed germination. PIL5 preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB). Analyses of a pil5 mutant in conjunction with phyA and phyB mutants, a pif3 pil5 double mutant, and PIL5 overexpression lines indicate that PIL5 is a negative factor in Phy-mediated promotion of seed germination, inhibition of hypocotyl negative gravitropism, and inhibition of hypocotyl elongation. Our data identify PIL5 as the first Phy-interacting protein that regulates seed germination.</description><subject>Arabidopsis - genetics</subject><subject>Arabidopsis - metabolism</subject><subject>Arabidopsis Proteins - genetics</subject><subject>Arabidopsis Proteins - metabolism</subject><subject>Arabidopsis thaliana</subject><subject>Basic Helix-Loop-Helix Transcription Factors</subject><subject>DNA-Binding Proteins - genetics</subject><subject>DNA-Binding Proteins - metabolism</subject><subject>Gene expression regulation</subject><subject>Germination</subject><subject>Germination - genetics</subject><subject>Gravitropism</subject><subject>Gravitropism - physiology</subject><subject>Helix-Loop-Helix Motifs - physiology</subject><subject>Hypocotyl - genetics</subject><subject>Hypocotyl - growth & development</subject><subject>Hypocotyl - metabolism</subject><subject>Hypocotyls</subject><subject>light</subject><subject>Mutation - physiology</subject><subject>Photoreceptor Cells - metabolism</subject><subject>photoreceptors</subject><subject>Physiological regulation</subject><subject>phytochrome</subject><subject>Phytochrome - metabolism</subject><subject>Phytochrome A</subject><subject>Phytochrome B</subject><subject>Plant cells</subject><subject>Plants</subject><subject>protein-protein interactions</subject><subject>Seed germination</subject><subject>seedling growth</subject><subject>Seedlings</subject><subject>Seeds - genetics</subject><subject>Seeds - metabolism</subject><subject>signal transduction</subject><subject>transcription factors</subject><subject>Transcription Factors - genetics</subject><subject>Transcription Factors - isolation & purification</subject><subject>Transcription Factors - metabolism</subject><issn>1040-4651</issn><issn>1532-298X</issn><issn>1532-298X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkktv1DAUhSMEomVgywqBxaKrZrh-xc6CRVVRqDQSSFCJneU4TsZDxg62p2J-AX8bw4zKY8PKVzrfsex7TlU9xbDEGPirPJslBrYEwnFD71WnmFNSk1Z-vl9mYFCzhuOT6lFKGwDAArcPqxPMmWwwkNPq-4frFT9HGs3rfQ5mHcPW1s5nG7XJzo-o08kZtLaT-1ZPIcz1rxHNMWTr_DlyqZi_2D3ydtTZ3VoU7bibdA4RhQEla3s02rh1vqjBI-fRRdSd68Ocijev9eS014-rB4Oekn1yPBfVzdWbT5fv6tX7t9eXF6vaMMlyjXkPg5DatD3XRHcaWtZ0g2DWENnxBjMJMPRdMzDaQsd7KllHpMS9AUNMRxfV68O9867b2t5Yn6Oe1BzdVse9CtqpvxXv1moMt4qTsjpR_GdHfwxfdzZltXXJ2GnS3oZdUo0A2kj6fxALASBLZovq5T_gJuyiL0tQBEshMBekQMsDZGJIKdrh7sUY1M8iqFKEMjN1KEIxPP_zn7_xY_IFeHYANqlEdadTKQiRrMgvDvKgg9JjdEndfCSAKUDbAMWM_gDJLsP8</recordid><startdate>20041101</startdate><enddate>20041101</enddate><creator>Oh, E</creator><creator>Kim, J</creator><creator>Park, E</creator><creator>Kim, J.I</creator><creator>Kang, C</creator><creator>Choi, G</creator><general>American Society of Plant Biologists</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7QO</scope><scope>7TM</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>RC3</scope><scope>S0X</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20041101</creationdate><title>PIL5, a phytochrome-interacting basic helix-loop-helix protein, is a key negative regulator of seed germination in Arabidopsis thaliana</title><author>Oh, E ; Kim, J ; Park, E ; Kim, J.I ; Kang, C ; Choi, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-15d0f78ac9d5a2aba0946bf74ec28b5614800fdb6f4390b5d384b2881dc0c2cb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Arabidopsis - genetics</topic><topic>Arabidopsis - metabolism</topic><topic>Arabidopsis Proteins - genetics</topic><topic>Arabidopsis Proteins - metabolism</topic><topic>Arabidopsis thaliana</topic><topic>Basic Helix-Loop-Helix Transcription Factors</topic><topic>DNA-Binding Proteins - genetics</topic><topic>DNA-Binding Proteins - metabolism</topic><topic>Gene expression regulation</topic><topic>Germination</topic><topic>Germination - genetics</topic><topic>Gravitropism</topic><topic>Gravitropism - physiology</topic><topic>Helix-Loop-Helix Motifs - physiology</topic><topic>Hypocotyl - genetics</topic><topic>Hypocotyl - growth & development</topic><topic>Hypocotyl - metabolism</topic><topic>Hypocotyls</topic><topic>light</topic><topic>Mutation - physiology</topic><topic>Photoreceptor Cells - metabolism</topic><topic>photoreceptors</topic><topic>Physiological regulation</topic><topic>phytochrome</topic><topic>Phytochrome - metabolism</topic><topic>Phytochrome A</topic><topic>Phytochrome B</topic><topic>Plant cells</topic><topic>Plants</topic><topic>protein-protein interactions</topic><topic>Seed germination</topic><topic>seedling growth</topic><topic>Seedlings</topic><topic>Seeds - genetics</topic><topic>Seeds - metabolism</topic><topic>signal transduction</topic><topic>transcription factors</topic><topic>Transcription Factors - genetics</topic><topic>Transcription Factors - isolation & purification</topic><topic>Transcription Factors - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oh, E</creatorcontrib><creatorcontrib>Kim, J</creatorcontrib><creatorcontrib>Park, E</creatorcontrib><creatorcontrib>Kim, J.I</creatorcontrib><creatorcontrib>Kang, C</creatorcontrib><creatorcontrib>Choi, G</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Biotechnology Research Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Science Journals</collection><collection>ProQuest Biological Science Journals</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Plant cell</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oh, E</au><au>Kim, J</au><au>Park, E</au><au>Kim, J.I</au><au>Kang, C</au><au>Choi, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PIL5, a phytochrome-interacting basic helix-loop-helix protein, is a key negative regulator of seed germination in Arabidopsis thaliana</atitle><jtitle>The Plant cell</jtitle><addtitle>Plant Cell</addtitle><date>2004-11-01</date><risdate>2004</risdate><volume>16</volume><issue>11</issue><spage>3045</spage><epage>3058</epage><pages>3045-3058</pages><issn>1040-4651</issn><issn>1532-298X</issn><eissn>1532-298X</eissn><abstract>The first decision made by an angiosperm seed, whether to germinate or not, is based on integration of various environmental signals such as water and light. The phytochromes (Phys) act as red and far-red light (Pfr) photoreceptors to mediate light signaling through yet uncharacterized pathways. We report here that the PIF3-like 5 (PIL5) protein, a basic helix-loop-helix transcription factor, is a key negative regulator of phytochrome-mediated seed germination. PIL5 preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB). Analyses of a pil5 mutant in conjunction with phyA and phyB mutants, a pif3 pil5 double mutant, and PIL5 overexpression lines indicate that PIL5 is a negative factor in Phy-mediated promotion of seed germination, inhibition of hypocotyl negative gravitropism, and inhibition of hypocotyl elongation. Our data identify PIL5 as the first Phy-interacting protein that regulates seed germination.</abstract><cop>United States</cop><pub>American Society of Plant Biologists</pub><pmid>15486102</pmid><doi>10.1105/tpc.104.025163</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Arabidopsis - genetics Arabidopsis - metabolism Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Arabidopsis thaliana Basic Helix-Loop-Helix Transcription Factors DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene expression regulation Germination Germination - genetics Gravitropism Gravitropism - physiology Helix-Loop-Helix Motifs - physiology Hypocotyl - genetics Hypocotyl - growth & development Hypocotyl - metabolism Hypocotyls light Mutation - physiology Photoreceptor Cells - metabolism photoreceptors Physiological regulation phytochrome Phytochrome - metabolism Phytochrome A Phytochrome B Plant cells Plants protein-protein interactions Seed germination seedling growth Seedlings Seeds - genetics Seeds - metabolism signal transduction transcription factors Transcription Factors - genetics Transcription Factors - isolation & purification Transcription Factors - metabolism |
| title | PIL5, a phytochrome-interacting basic helix-loop-helix protein, is a key negative regulator of seed germination in Arabidopsis thaliana |
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