NtcA—A negative regulator of secondary metabolite biosynthesis in Sorangium cellulosum

Microorganisms continue to be a source of novel, bioactive natural products for the treatment of human diseases. Notable among them are the myxobacteria, with some 50% of metabolites isolated from strains of a single species, Sorangium cellulosum. As native production in myxobacteria is often low, h...

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Veröffentlicht in:	Journal of biotechnology 2009-03, Vol.140 (1), p.135-142
Hauptverfasser:	Rachid, S., Gerth, K., Müller, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - genetics Bacterial Proteins - metabolism Cell Differentiation Chivosazol Chromatography, High Pressure Liquid DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene Expression Regulation, Bacterial Genomics Macrolides - metabolism Mass Spectrometry Molecular Sequence Data Myxobacteria Myxococcales - genetics Myxococcales - metabolism Nitrogen - metabolism NtcA Polyenes - metabolism Quaternary Ammonium Compounds - metabolism Regulation Secondary metabolism Sequence Alignment Sorangium cellulosum Transcription Factors - genetics Transcription Factors - metabolism
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